Medication info
Notension Tablet 2.5 mg (Esamlodipine Besilate Hydrate)

Notension Tablet 2.5 mg (Esamlodipine Besilate Hydrate)

Prescription medicationTablet경구
Ingredient · strength
S-Amlodipine Besylate Dihydrate›3.69mg / 1 tablet
Manufacturer / importer
(주)비보존제약
Appearance
White octagonal tablet
Packaging
30 tablets/bottle, 300 tablets/bottle
Approval status
Active

MFDS item code 201800048 · Approved 2018.01.04 · Insurance code 658203990

Summary

Main use
Improvement of hypertension and myocardial ischemia (stable angina, variant angina)
Who takes it
Adults
Adult dose
This medication should be taken with a sufficient amount of water. As esamlodipine, administer 2.5 mg orally once daily, and may increase to a maximum of 5 mg daily based on patient response. Adjust dosages appropriately according to symptoms.

Ingredients

Manufacturer
(주)비보존제약

Efficacy & effects

Improvement of hypertension and myocardial ischemia (stable angina, variant angina)

  • Hypertension
  • fixed occlusion of coronary arteries
  • vascular spasms in coronary circulation
  • myocardial ischemia
View approved original text

This medication is effective for the treatment of hypertension and is also used for myocardial ischemia due to stable and variant angina. It helps to control blood pressure and improve blood flow to the heart, alleviating symptoms. This drug is used to maintain cardiovascular health and reduce discomfort for patients.

How to take

Adult dose

This medication should be taken with a sufficient amount of water. As esamlodipine, administer 2.5 mg orally once daily, and may increase to a maximum of 5 mg daily based on patient response. Adjust dosages appropriately according to symptoms.

Precautions

This medication should not be administered to certain patients. For example, it should not be used in individuals who are allergic to this medication or its components, in pregnant or breastfeeding women, and in patients with severe heart problems or liver dysfunction. Caution should be exercised when administering to patients with severely impaired kidney function, the elderly, those with acute heart failure, and patients with severe liver dysfunction. During the use of this medication, side effects such as flushing, fatigue, swelling, palpitations, dizziness, headaches, and dyspepsia may occur, and if symptoms are severe, consulting a doctor is advised. Particularly, patients with liver dysfunction should have their liver enzyme levels checked regularly, and if abnormalities are detected, the medication should be discontinued. Abrupt discontinuation of this medication may worsen symptoms, so the dosage should be gradually reduced under medical supervision, and patients should be careful not to stop taking it on their own. Take this medication with a sufficient amount of water, and if symptoms such as dizziness or drowsiness occur, avoid driving or operating hazardous machinery. This medication may interact with other antihypertensive drugs, certain antibiotics, and antidepressants, so it is essential to inform the doctor or pharmacist of any medications being taken together. In particular, taking it with grapefruit juice may enhance its effects, so it is advisable to avoid this combination. If pregnant or breastfeeding, the safety of this medication has not been established, and its use should be avoided, and it is recommended to discontinue breastfeeding if nursing. In children, it is recommended only for those aged 6 years and older, and its effects have not been established in those under 6. In case of overdose, severe hypotension, heart problems, shock, etc., may occur, so immediate medical attention is required. Finally, this medication should be stored out of the reach of children, and it is safest not to transfer it to other containers.

Side effects and when to seek care immediately

Serious side effects

  • Hives, angioedema, toxic epidermal necrolysis, severe allergic reactions
  • Hepatitis, jaundice, elevated liver enzymes, liver abnormalities (jaundice)
  • Paralysis, severe neurological symptoms
  • Shortness of breath, difficulty breathing, asthmatic attack, cough, breathing difficulties accompanied by fever
  • Significantly decreased urine output, severe systemic edema, elevated blood pressure.

Mild side effects

  • Flushing accompanied by warmth
  • fatigue
  • swelling
  • palpitations
  • dizziness
  • headaches
  • migraines
  • weakness
  • abdominal pain
  • nausea
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  • dyspepsia
  • drowsiness
  • dry mouth
  • increased sweating
  • weakness
  • lethargy
  • pain
  • weight gain or loss
  • chills
  • hypotension
  • orthostatic hypotension
  • positional dizziness
  • peripheral ischemia
  • vasculitis
  • syncope
  • tachycardia
  • peripheral edema
  • tension increase
  • sensory loss
  • paresthesia
  • peripheral neuropathy
  • altered taste
  • tremors
  • paralysis
  • extrapyramidal disorders
  • and more.

Not everyone experiences these, and they can vary from person to person.

Storage

This medication may be sensitive to air or moisture, so it should be stored in a tightly closed container. It is best to maintain a storage temperature between 1°C and 30°C. This will help ensure the medication's effectiveness.

Appearance and packaging

Appearance

White octagonal tablet

Package unit

30 tablets/bottle, 300 tablets/bottle

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

Questions about this medicine

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For anything that needs medical judgment, consult a doctor or pharmacist.

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.