Medication info
Ejitension Tablets (S-Amlodipine Besylate 2.5 Hydrate)

Ejitension Tablets (S-Amlodipine Besylate 2.5 Hydrate)

Prescription medicationTablet경구
Ingredient · strength
S-Amlodipine Besylate 2.5 Hydrate›3.74mg / 1 tablet
Manufacturer / importer
(주)마더스제약
Appearance
Pale yellow hexagonal tablet with a score line
Packaging
30 tablets/bottle, 200 tablets/bottle
Approval status
Active

MFDS item code 201708627 · Approved 2017.12.29 · Insurance code 622803110

Summary

Main use
Improvement of hypertension and myocardial ischemia (stable angina, variant angina)
Who takes it
Adults
Adult dose
This medication should be taken with a sufficient amount of water. S-Amlodipine should be administered orally at a dose of 2.5 mg once a day, which can be increased to a maximum of 5 mg per day based on the patient’s response. The dosage can be adjusted appropriately according to symptoms.

Ingredients

Manufacturer
(주)마더스제약

Efficacy & effects

Improvement of hypertension and myocardial ischemia (stable angina, variant angina)

  • Hypertension
  • fixed coronary obstruction
  • stable angina
  • coronary vascular spasm
  • variant angina
  • myocardial ischemia
View approved original text

This medication is used for hypertension as well as stable angina caused by fixed coronary obstruction and variant angina due to vascular spasm of the coronary arteries. These conditions arise from insufficient blood supply to the heart, and this drug helps alleviate symptoms and reduce the burden on the heart by dilating blood vessels and improving blood flow. Therefore, it effectively aids patients with hypertension or angina.

How to take

Adult dose

This medication should be taken with a sufficient amount of water. S-Amlodipine should be administered orally at a dose of 2.5 mg once a day, which can be increased to a maximum of 5 mg per day based on the patient’s response. The dosage can be adjusted appropriately according to symptoms.

Precautions

This medication should not be used by certain patients. For example, patients with a history of allergies to this drug or similar medications, women who are pregnant or may become pregnant, nursing women, patients in severe shock, those with severe aortic stenosis, unstable angina patients, recent myocardial infarction patients, patients with severe liver dysfunction, those with severe hypotension, and patients with genetic issues such as lactose intolerance may risk harm from taking this drug. Patients with severe kidney dysfunction, elderly individuals, those in acute heart failure, hypertensive crisis patients, or those with mild to moderate liver dysfunction should use this medication cautiously. While taking this drug, side effects such as flushing, fatigue, swelling, palpitations, dizziness, headache, indigestion, drowsiness, and ankle swelling may occur. Rarely, hypotension, skin rash, liver dysfunction, and allergic reactions can develop, so immediate consultation with a healthcare professional is necessary if symptoms appear. Abrupt discontinuation of this drug may worsen symptoms, so the dosage should be gradually reduced under the guidance of a physician, and patients should avoid stopping the medication on their own. Take it with a sufficient amount of water, and caution should be exercised when driving or operating hazardous machinery due to potential dizziness from the blood pressure-lowering effects. Drug interactions may occur when used with other medications, so it is crucial to consult a physician when taking it, especially in conjunction with certain antibiotics, blood pressure medications, antidepressants, or nitrate preparations. Safety has not been established for use during pregnancy or breastfeeding, so it should be avoided, and breastfeeding is recommended to be discontinued while taking this medication. Use in children is only recommended for those aged 6 years and older, and elderly patients should start with a lower dose due to the potential for increased drug concentration. In case of overdose, severe hypotension or cardiac issues may occur, necessitating immediate medical attention. Lastly, this medication should be kept out of reach of children, and it is safe not to transfer it to another container.

Side effects and when to seek care immediately

Serious side effects

  • Urticaria
  • angioedema
  • Stevens-Johnson syndrome
  • toxic epidermal necrolysis
  • chest tightness
  • difficulty breathing
  • severe swelling (edema)
  • jaundice (yellowing of the skin or eyes)
  • extreme lethargy
  • paralysis
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  • severe allergic reactions
  • severe skin reactions
  • respiratory issues
  • liver abnormalities (jaundice)
  • severe neurological symptoms
  • severe swelling
  • or urinary issues

Mild side effects

  • Flushing with a sense of heat
  • fatigue
  • swelling
  • palpitations
  • dizziness
  • headache
  • migraine
  • weakness
  • abdominal pain
  • nausea
Show 25 more
  • indigestion
  • drowsiness
  • dry mouth
  • increased sweating
  • weakness
  • lethargy
  • pain
  • weight gain/loss
  • chills
  • hypotension
  • orthostatic hypotension
  • positional dizziness
  • peripheral ischemia
  • vasculitis
  • syncope
  • tachycardia
  • peripheral edema
  • anxiety
  • sensory impairment/sensory abnormalities
  • peripheral neuropathy
  • taste disturbance
  • tremors
  • paralysis
  • extrapyramidal disorder
  • erectile dysfunction

Not everyone experiences these, and they can vary from person to person.

Storage

This medication may be sensitive to air or moisture, so it should be stored in a sealed container. Additionally, it is best to keep the medication at room temperature, between 1 to 30 degrees Celsius, rather than in extremely hot or cold environments. This helps maintain the drug's efficacy for a longer duration.

Appearance and packaging

Appearance

Pale yellow hexagonal tablet with a score line

Package unit

30 tablets/bottle, 200 tablets/bottle

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

Questions about this medicine

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For anything that needs medical judgment, consult a doctor or pharmacist.

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.