Cardien Tablet 5/20 mg

Adult dose

Amlodipine (esamlodipine): Administer 5 (2.5) mg orally once daily, and the dose may be increased to a maximum of 10 (5) mg daily according to the patient's response. Adjust as needed based on symptoms. Atorvastatin: For patients with primary hypercholesterolemia and mixed dyslipidemia, the recommended initial dose is 10 mg once daily, and it may be increased to 20 mg or 40 mg daily as needed.

This medication should not be used in certain patients. For example, it should not be administered to those with allergies to this drug or similar substances, severe liver impairment, women who are pregnant or breastfeeding, patients with severe muscle diseases, severe aortic stenosis, patients in cardiogenic shock, or patients within 1 month post-myocardial infarction. Caution should be exercised in patients with severe kidney impairment, the elderly, alcoholics, patients with a history of liver disease, those at risk for muscle disorders, patients with acute heart failure, or those in hypertensive crisis. Since muscle-related adverse effects may occur, muscle damage should be monitored through blood tests during administration. While this medication is generally well tolerated by most patients, it may cause mild adverse reactions such as flushing, fatigue, edema, dizziness, headache, and nausea. Rarely, liver function abnormalities, myalgia, allergic reactions, and skin rashes may occur, and if any abnormal symptoms arise, the doctor should be consulted immediately. Regular liver function tests are required during the use of this medication, and if symptoms such as hepatitis, myalgia, muscle weakness, or dizziness occur, medical personnel should be informed immediately. Women who are pregnant or may become pregnant should consult with a healthcare professional before taking this medication and should ensure appropriate contraception. It is also recommended that breastfeeding women do not take this medication. This medication may interact with other drugs, so if you are taking other medications, you must inform your healthcare professional. Caution is particularly important when used in conjunction with certain antibiotics, antifungals, immunosuppressants, HIV treatments, and some lipid-lowering agents. In case of overdose, there is a risk of severe hypotension, arrhythmias, and shock, and emergency treatment should be sought immediately, as dialysis may not be effective. The safety and efficacy of this medication have not been sufficiently established in children or the elderly, so use should be cautious in these age groups. Store in a place out of children's reach and do not transfer to another container.

Serious side effects

Hives, severe swelling (edema), toxic epidermal necrolysis, severe allergic reactions, severe skin reactions, difficulty breathing, respiratory distress, asthma attacks, liver abnormalities (jaundice), yellowing of the skin or eyes (jaundice), sudden and severe headache, seizures, confusion, vision changes, paralysis, serious neurological symptoms, significant reduction in urine output, generalized severe swelling, and elevated blood pressure associated with severe edema or

Mild side effects

• Flushing
• fatigue
• edema
• palpitations
• dizziness
• headache
• drowsiness
• abdominal pain
• nausea
• weakness

This medication may be sensitive to air or moisture, so it should be stored in a tightly closed container. The storage temperature should be maintained between 15 and 30 degrees Celsius. This helps to safely preserve the medication's efficacy for a prolonged period.

Appearance

White oval film-coated tablet

Package unit

30 tablets/bottle