Proban Tablet 20 mg (Propiverine Hydrochloride)

Adult dose

Adults: Administer 20 mg of propiverine hydrochloride orally once daily after a meal. The dose may be adjusted according to symptoms. If the effect is inadequate and there are no safety concerns, 20 mg may be taken up to twice daily.

This medication should not be used in certain patients. For example, individuals allergic to this medication or its ingredients, patients with obstruction in the stomach or intestines, those with weak gastrointestinal motility, patients with difficulty urinating, individuals with glaucoma, patients with severe myasthenia gravis, patients with serious heart problems, individuals with severely impaired liver function, and those with arrhythmias may experience worsening symptoms if they take this medication and should avoid it. Furthermore, this medication contains lactose, so it should not be administered to patients with lactose intolerance or specific genetic metabolic disorders. There are also patients who should be cautious when taking this medication. Those with urinary difficulties, liver or kidney problems, patients with Parkinson's disease or cerebrovascular disease, patients with hyperthyroidism, the elderly, and individuals with autonomic nervous system disorders or heart diseases may experience symptom worsening or side effects, requiring caution. This medication can cause various side effects. Mentally, hallucinations or delusions may occur, and rarely, intestinal obstruction, heart abnormalities, blood disorders, kidney function decline, skin rashes, acute glaucoma attacks, liver dysfunction, muscle pain, or rhabdomyolysis can happen. If any of these symptoms appear, immediately stop taking the medication and consult with a healthcare professional. During use, it is necessary to check for other conditions such as bladder cancer, prostate cancer, urinary tract infections, or urinary calculi, and complications of urinary tract obstruction due to benign prostatic hyperplasia should be treated as a priority. This medication may cause drowsiness, dizziness, or visual disturbances, so it is advisable to avoid driving or operating dangerous machinery. Additionally, caution is needed when taken with anticholinergics, tricyclic antidepressants, phenothiazines, or MAO inhibitors as side effects may increase. Women who are pregnant or may become pregnant are advised not to take this medication, and breastfeeding women should also refrain from nursing while on this medication. Safety in pediatric populations has not been established, therefore it is recommended not to administer it to children. In the elderly, liver and kidney functions may be decreased, so it should be started cautiously from a low dose. In cases of overdose, symptoms such as delusions, seizures, gait disturbances, urination problems, heart abnormalities, and liver dysfunction may occur, requiring prompt medical treatment. This medication should be stored out of reach of children, and transferring it to another container may pose risks of accidents and quality degradation.

• Hallucinations
• delusions
• paralytic ileus
• significant constipation
• abdominal distension
• palpitations
• extrasystole
• bradycardia
• QT prolongation
• ventricular tachycardia

This medication should be stored in a sealed container to prevent air ingress, ideally at room temperature between 1°C and 30°C. Proper storage will help maintain the medication's efficacy for a long time.

Appearance

White round film-coated tablet

Package unit

30 tablets/bottle, 100 tablets/bottle