Lipiclin Tablets 20 mg (Atorvastatin Calcium Trihydrate)

Adult dosage

The recommended initial dose for patients with hyperlipidemia is 10 mg of atorvastatin once daily. If greater reduction in LDL cholesterol is needed, it can be started at 20 mg or 40 mg once daily. This medication is administered within a dosage range of 10 to 80 mg once daily. After starting treatment and adjusting the dosage, lipid levels should be analyzed within 2 to 4 weeks, and the dosage should be adjusted accordingly. The treatment goal is to reduce LDL cholesterol levels; thus, it is recommended to use LDL cholesterol for assessing treatment response at the beginning of treatment and for evaluating treatment responsiveness. However, if LDL cholesterol levels cannot be monitored, total cholesterol levels may be used to track treatment response. For patients with homozygous familial hypercholesterolemia, the dosage is 10 to 80 mg once daily, and this medication is used in conjunction with other lipid-lowering treatments (e.g., LDL apheresis) or when such treatments are not possible.

Children's dosage

The recommended initial dose for pediatric patients (10 to 17 years) with heterozygous familial hypercholesterolemia is 10 mg once daily, and the recommended maximum dose is 20 mg once daily. Dosage adjustments should be made with an interval of more than 4 weeks.

This medication may cause muscle-related adverse effects; if severe muscle pain or weakness occurs or if creatine kinase levels rise significantly, discontinue use immediately and consult a physician. Particularly, patients with serious infections, hypotension, prior major surgery or trauma, or liver or kidney dysfunction may need to temporarily pause or stop treatment. Patients with a history of allergic reactions to this medication, active liver disease, severe muscle disorders, those who are pregnant or nursing, children under 10 years, and patients taking certain medications should not use it. Patients with alcoholism, a history of liver disease, impaired kidney function, hypothyroidism, and elderly patients, who are at higher risk of muscle damage, require careful evaluation before use. During treatment, regular liver function tests and muscle-related tests should be conducted, and any abnormal symptoms should be reported to medical personnel immediately. This medication can interact with several drugs; therefore, patients should inform their doctor or pharmacist if they are taking other medications. Particular caution is needed when used in conjunction with certain antibiotics, antifungal agents, HIV medications, some antihypertensive drugs, and hypoglycemic agents. Women of childbearing age should use appropriate contraception during use and immediately discontinue use if pregnant. Nursing women should avoid using this medication, and special caution is necessary for children and elderly patients as well. There is no specific antidote for overdose; treatment should be symptomatic, and it should be stored out of reach of children.

Serious side effects

Hives, severe swelling (edema), chest tightness, difficulty breathing, cold sweat, pallor, severe allergic reaction, rash with high fever, blisters, skin peeling, pain in mucous membranes of the mouth/eyes, severe skin reactions, shortness of breath or difficulty breathing, asthma attacks, respiratory abnormalities accompanied by cough and fever, respiratory problems, yellowing of the skin or eyes (jaundice), extreme lethargy, liver issues (jaundice), sudden onset of

Mild side effects

• Fatigue
• lethargy
• chest pain
• peripheral edema
• tiredness
• fever
• nasopharyngitis
• hyperglycemia
• hypoglycemia
• weight gain

This medication should be stored in a tightly closed container to protect it from air and moisture. The storage temperature should be kept between 1 degree and 30 degrees Celsius.

Appearance

White round film-coated tablet

Package unit

30 tablets/bottle, 300 tablets/bottle