Mecobalamin (Mecobalamin)

Adult dosage

1. Peripheral neuropathy Adults: Administer 500 ㎍ of Mecobalamin once daily, by intramuscular or intravenous injection 3 times a week. 2. Megaloblastic anemia Adults: Administer 500 ㎍ of Mecobalamin once daily, by intramuscular or intravenous injection 3 times a week. Upon symptom resolution, administer 500 ㎍ intramuscularly or intravenously once every 1-3 months. Adjust dose according to age and symptoms.

Care should be taken while cutting this medication as there is a risk of glass fragments from the glass ampoule mixing in. Extra caution is necessary, especially when used on children or the elderly. Do not administer to patients with allergies to the ingredients contained in this medication. It should be administered with caution in pregnant or breastfeeding women. If allergic reactions such as skin rashes occur while using this medication, it should be stopped immediately. Additionally, due to the possibility of low potassium levels in the blood leading to cardiac arrhythmias during initial treatment, regular monitoring of blood potassium levels is necessary. Hard lumps may develop at the injection site, and sweating and a warm sensation can occur, along with pain or headache. If serious allergic reactions such as low blood pressure or difficulty breathing occur, the medication should be stopped immediately and appropriate emergency measures should be taken. This medication should not be used for more than one month if it does not improve anemia or neurological disorders caused by vitamin B12 deficiency. Since vitamin B12 deficiency can occur alongside other vitamin deficiencies, a comprehensive nutritional assessment should be considered. Before administration, confirm the presence of vitamin B12 deficiency, and caution is required for patients with folic acid deficiency as blood anomalies may occur with doses exceeding a certain level. If anemia does not improve after treatment, suspect folate metabolism disorders and further investigation may be necessary. Regular blood testing should be conducted to monitor the condition. Certain antibiotics or anticancer drugs may affect the diagnostic test results of this medication, and specific drugs may reduce its efficacy. In pregnant women, it should only be administered if anemia caused by vitamin B12 deficiency is confirmed. This medication is sensitive to light, so it should be taken out from a light-blocking container just before use, and the injection site should be carefully selected to avoid nerve or tissue damage during intramuscular injection. Avoid repeated injections at the same site, and extreme caution is needed especially for infants or children. If severe pain occurs during the injection or if blood reflux happens, the needle should be withdrawn immediately, and the injection should be given at a different site. Before opening the ampoule, the cut surface should be thoroughly cleaned with an alcohol swab. Store this medication out of reach of children, and keep it shaded at room temperature below 30 degrees Celsius. Also, store it in the original container to prevent misuse or quality deterioration.

Serious side effects

Symptoms of hypersensitivity, anaphylactic-like reactions (low blood pressure, difficulty breathing)

Mild side effects

• Induration at the injection site
• sweating
• warm sensation
• pain at the injection site
• headache

This medication should be stored in a sealed container that blocks light, and it is recommended to keep it at room temperature between 1 degree Celsius and 30 degrees Celsius. This storage method helps to maintain the medication's effectiveness.

Appearance

A brown ampoule containing a transparent liquid of dark red color

Package unit

1mL/ampoule x 50