Medication info
Dexiar 480 mg (Alpha-Lipoic Acid Trimetazidine Salt)

Dexiar 480 mg (Alpha-Lipoic Acid Trimetazidine Salt)

Prescription medicationTabletOral
Ingredient · strength
R-Thioctic Acid Tromethamine›480mg / 1 tablet
Manufacturer / importer
Ajou Pharmaceutical Co., Ltd.
Appearance
Greenish rectangular film-coated tablet
Packaging
30 tablets/bottle, 100 tablets/bottle
Approval status
Active

MFDS item code 201708456 · Approved 2017.12.20 · Insurance code 654004980

Summary

Main use
Relief of diabetic polyneuropathy
Who takes it
Adults
Adult dose
Adults: Take 480 milligrams of thioctic acid tromethamine salt once daily with plenty of water, approximately 30 minutes before breakfast.

Ingredients

Manufacturer
Ajou Pharmaceutical Co., Ltd.

Efficacy & effects

Relief of diabetic polyneuropathy

  • Diabetic polyneuropathy
View approved original text

This medication helps alleviate nerve damage and pain caused by diabetic polyneuropathy. Patients can expect improvement in nerve function and a reduction in uncomfortable symptoms by using this medication. It contributes to overall nerve health, enhancing quality of life. Therefore, it is used to relieve symptoms of diabetic polyneuropathy.

How to take

Adult dose

Adults: Take 480 milligrams of thioctic acid tromethamine salt once daily with plenty of water, approximately 30 minutes before breakfast.

Precautions

This medication should not be used by individuals allergic to Alpha-Lipoic Acid Trimetazidine Salt or Thioctic Acid, or any other components contained in this medication. During the course of this medication, side effects such as sensory disturbances, pain, headache, constipation, and dry mouth may occur, and rarely serious adverse reactions such as kidney stones may also appear. Additionally, some patients taking this medication have reported symptoms such as dry mouth, muscle pain, nausea, decreased appetite, and insomnia. After long-term use of this medication, rare symptoms such as muscle pain, thyroiditis, blood sugar abnormalities, urination difficulties, skin rashes, hives, and hypoglycemic symptoms may appear, so caution is advised. Individuals who frequently consume alcohol may experience reduced therapeutic effects of this medication, so it is recommended to avoid alcohol as much as possible. This medication may interact with iron, magnesium preparations, milk, etc., causing a reduction in efficacy. Therefore, it is recommended to take it 30 minutes before meals and to take iron or magnesium preparations after meals. Additionally, when taken in conjunction with insulin or other diabetes medications, blood sugar levels may drop too low; therefore, blood sugar levels should be monitored frequently, and medication dosages may need to be adjusted as necessary. Pregnant or breastfeeding women should consult with their doctor to carefully evaluate the benefits and risks of using this medication. There is no experience in using this medication in individuals under 18 years old, so it is safer to avoid administering it to children. In case of an overdose of this medication, symptoms such as altered consciousness, general seizures, and hypoglycemic symptoms may occur, necessitating immediate medical attention and appropriate treatment. This medication should not be stored at temperatures above 30 degrees Celsius and should be kept in a safe place out of reach of children, preferably in its original container.

Side effects

  • paresthesia
  • pain
  • sensory loss
  • headache
  • constipation
  • abdominal discomfort
  • nasopharyngitis
  • dry mouth
  • cough
  • cystitis
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  • diarrhea
  • burning sensation
  • nephrolithiasis
  • lumbar canal stenosis
  • facial swelling
  • dry mouth
  • muscle pain
  • nausea
  • loss of appetite
  • joint pain
  • palpitations
  • insomnia
  • upper limb fracture
  • hypoglycemia
  • neurogenic bladder
  • diabetic retinopathy
  • colitis
  • benign gastric neoplasm
  • gastrointestinal bleeding
  • worsening of disease
  • soft tissue inflammation
  • cold
  • body pain
  • plantar fasciitis
  • herniated disc
  • thyroiditis
  • increased LDH
  • increased triglycerides
  • weight loss
  • blood sugar abnormalities
  • shingles
  • dysuria
  • worsening of renal function impairment
  • vaginitis
  • conjunctivitis
  • floaters
  • unspecified retinal vascular disorder
  • heart palpitations
  • acute abdominal symptoms
  • colon polyp
  • benign oral neoplasm
  • benign gastrointestinal neoplasm
  • gastroesophageal reflux disease
  • gastritis
  • enteritis
  • dental caries
  • periodontitis
  • anal bleeding
  • chest pain
  • peripheral edema
  • edema
  • limb pain
  • carpal tunnel syndrome
  • flank pain
  • generalized edema
  • generalized weakness
  • back pain
  • sleep disorders
  • simple partial seizure
  • facial paralysis
  • bitter taste
  • genital itching
  • nail changes
  • blisters
  • dermatitis
  • unspecified peripheral vascular disease
  • gum bleeding
  • sputum disorders
  • bronchitis
  • throat infections
  • sinusitis
  • congestion
  • upper respiratory tract infection
  • allergic atopic rhinitis
  • dyspnea
  • nausea
  • vomiting
  • gastrointestinal pain
  • skin rash
  • hives
  • itching
  • dizziness
  • sweating
  • taste disorders
  • epigastric pain
  • dyspepsia
  • pruritus
  • abdominal pain
  • heartburn

Not everyone experiences these, and they can vary from person to person.

Storage

This medication should be stored in a tightly closed container to protect it from air and moisture and should be kept at room temperature between 1 degree and 30 degrees Celsius. Proper storage will help maintain the medication's effectiveness and prevent deterioration.

Appearance and packaging

Appearance

Greenish rectangular film-coated tablet

Package unit

30 tablets/bottle, 100 tablets/bottle

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

Questions about this medicine

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For anything that needs medical judgment, consult a doctor or pharmacist.

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.