Medication info
Alpha-lipoic Acid 480 mg (R-lipoic Acid Tromenamine Salt)

Alpha-lipoic Acid 480 mg (R-lipoic Acid Tromenamine Salt)

Prescription medicationTablet
Ingredient · strength
R-Thioctic Acid Tromethamine›480mg / 1 tablet
Manufacturer / importer
Jongkundang Co., Ltd.
Appearance
Light green oblong film-coated tablet
Packaging
30 tablets/bottle, 100 tablets/bottle
Approval status
Active

MFDS item code 201708449 · Approved 2017.12.20 · Insurance code 643307970

Summary

Main use
Relief of diabetic polyneuropathy
Who uses it
Adults
Adult dosage
Adults: Take 480 milligrams of thioctic acid tromethamine salt once daily with plenty of water, approximately 30 minutes before breakfast.

Ingredients

Manufacturer
Jongkundang Co., Ltd.

Efficacy & effects

Relief of diabetic polyneuropathy

  • Diabetic Polyneuropathy
View approved original text

This medication helps alleviate uncomfortable symptoms caused by diabetic polyneuropathy. It reduces pain or sensory abnormalities due to nerve damage, improving the patient’s daily life to be more comfortable.

Dosage and Administration

Adult dosage

Adults: Take 480 milligrams of thioctic acid tromethamine salt once daily with plenty of water, approximately 30 minutes before breakfast.

Precautions

This medication should not be used in patients who are hypersensitive to R-lipoic Acid Tromenamine Salt. When taking this medication, side effects such as sensory abnormalities, pain, headaches, constipation, and dry mouth may occur, so caution is advised. Rarely, serious adverse reactions such as renal calculi may occur, and if symptoms arise, you should consult a healthcare professional immediately. It is advisable to avoid alcohol during treatment, as alcohol may reduce the therapeutic effects of this medication and worsen nerve damage. This medication's absorption may be hindered if taken with preparations containing iron, magnesium, calcium, or milk, so the timing of meals and medication should be adjusted accordingly. When taken together with diabetes medications, there is a risk of blood sugar dropping too low, so blood sugar should be checked frequently, and medication dosages should be adjusted as needed. For those who are pregnant or breastfeeding, this medication should only be used after careful evaluation of its benefits and risks, following the guidance of a physician. It is advisable not to administer this medication to children under 18, as safety has not been established. In case of overdose, serious poisoning symptoms such as confusion, seizures, and hypoglycemia may occur, necessitating immediate medical attention. This medication should be stored at temperatures not exceeding 30 degrees and kept in a safe place out of reach of children. Additionally, transferring this medication to another container may lead to degradation of quality, so it is safest to keep it in its original container.

Side effects

  • Paresthesia
  • pain
  • sensory loss
  • headache
  • constipation
  • abdominal discomfort
  • nasopharyngitis
  • dry mouth
  • cough
  • cystitis
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  • diarrhea
  • burning sensation
  • nephrolithiasis
  • dry mouth
  • myalgia
  • nausea
  • appetite loss
  • arthralgia
  • palpitations
  • insomnia
  • upper limb fractures
  • hypoglycemia
  • neurogenic bladder
  • diabetic retinopathy
  • colitis
  • benign gastric neoplasm
  • gastrointestinal bleeding
  • worsening of the disease
  • soft tissue infection
  • cold
  • body aches
  • plantar fasciitis
  • herniated disc
  • thyroiditis
  • increased LDH
  • increased triglycerides
  • weight loss
  • blood sugar abnormalities
  • herpes zoster
  • dysuria
  • worsening of renal function
  • vaginitis
  • conjunctivitis
  • floaters
  • unspecified retinal vascular disorder
  • heart palpitations
  • acute abdominal symptoms
  • colon polyps
  • benign oral neoplasm
  • benign gastrointestinal neoplasm
  • gastroesophageal reflux disease
  • gastritis
  • gastroenteritis
  • cavities
  • periodontitis
  • anal bleeding
  • chest pain
  • peripheral edema
  • edema
  • limb pain
  • carpal tunnel syndrome
  • flank pain
  • generalized edema
  • general weakness
  • back pain
  • sleep disorders
  • simple partial seizures
  • facial paralysis
  • bitter taste
  • genital pruritus
  • nail changes
  • vesicles
  • dermatitis
  • unspecified peripheral vascular disease
  • gum bleeding
  • sputum disease
  • bronchitis
  • throat infection
  • sinusitis
  • congestion
  • upper respiratory infection
  • allergic atopic rhinitis
  • dyspnea
  • nausea
  • vomiting
  • gastrointestinal pain
  • skin rash
  • urticaria
  • itching
  • dizziness
  • sweating
  • taste disorder
  • epigastric pain
  • dyspepsia
  • pruritus
  • abdominal pain
  • heartburn

Not everyone experiences these, and they can vary from person to person.

Storage

This medication may be sensitive to air or moisture, so it should be stored in a tightly sealed container. Furthermore, it is best to store it at room temperature between 1 degree and 30 degrees. Storing it this way will help maintain its effectiveness safely.

Appearance and packaging

Appearance

Light green oblong film-coated tablet

Package unit

30 tablets/bottle, 100 tablets/bottle

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

Questions about this medicine

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For anything that needs medical judgment, consult a doctor or pharmacist.

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.