K-Duet Tablet 5/20 Milligrams

Adult dose

For Amlodipine (as Esamlodipine), the initial dosage is 5 (2.5) mg orally once daily, which can be increased up to 10 (5) mg daily according to the patient’s response. Atorvastatin starts at 10 mg once daily and may be increased to 20 mg or 40 mg once daily as needed. Dosage should be individualized based on treatment goals and patient response, with lipid levels monitored every 2 to 4 weeks.

This medication should not be used in specific patients. For example, it should not be administered to patients who are allergic to this medication or similar drugs, those with severe liver dysfunction, pregnant or breastfeeding women, individuals with severe muscle disorders, or those with severe aortic stenosis or in a state of shock. Additionally, patients with very poor kidney function, the elderly, alcoholics, those with a history of liver disease, or those at risk of specific muscle disorders should use this medication with more caution. Generally, this medication is well tolerated, but mild side effects such as fatigue, edema, dizziness, headache, and dyspepsia may occur. Rarely, skin rash, liver function abnormalities, and myalgia may occur, so if symptoms worsen, it is important to inform medical personnel immediately. This medication is known not to significantly impair driving or machine operation abilities; however, dizziness or drowsiness may rarely occur, so caution is needed. This medication may interact with other drugs, so if you are currently taking any medications, you must inform healthcare professionals. Special caution is required when used with drugs that affect liver function or those with muscle toxicity risks. Women who are pregnant or may become pregnant should use appropriate contraception while taking this medication and should discontinue it immediately upon confirmation of pregnancy. Breastfeeding women should also not take this medication. Safety in children and the elderly has not been sufficiently confirmed; therefore, use should be according to the advice of a specialist. In case of overdose, severe hypotension or decreased heart function may occur, necessitating immediate visit to a medical institution for proper emergency treatment. This medication should be kept out of the reach of children and should not be transferred to another container.

Serious side effects

Hives, severe swelling (edema), angioedema, severe allergic reactions, toxic epidermal necrolysis, severe skin adverse reactions, jaundice, hepatitis, severe liver abnormalities, elevated liver enzymes, fulminant hepatitis, cholestasis, cholestatic jaundice, liver damage, hemorrhagic stroke, myocardial infarction, arrhythmias, worsening heart failure, severe hypotension, shock, asthma attacks, dyspnea, pulmonary edema, severe neurological symptoms (severe headache, confusion, seizures, visual disturbances).

Mild side effects

• Flushing
• fatigue
• edema
• palpitations
• dizziness
• headache
• drowsiness
• abdominal pain
• nausea
• weakness

This medication must be stored in a tightly closed container to prevent exposure to air or moisture. It is important to maintain a room temperature between 15 and 30 degrees Celsius.

Appearance

White oval film-coated tablets

Package unit

30 tablets/bottle