Medication info
Retium Tablet 500 Milligrams (Dovessilic Acid Calcium Hydrate)

Retium Tablet 500 Milligrams (Dovessilic Acid Calcium Hydrate)

Prescription medicationTabletOral
Ingredient · strength
Dobesilate Calcium Hydrate›500mg / 1 tablet
Manufacturer / importer
Kukje Pharmaceutical Co., Ltd.
Appearance
White oval film-coated tablet
Packaging
30 tablets/bottle, 90 tablets/bottle
Approval status
Active

MFDS item code 201708126 · Approved 2017.11.29 · Insurance code 643705160

Summary

Main use
Treatment of capillary disorders (e.g., diabetic retinopathy), venous diseases (e.g., edema), and hemorrhoids
Who takes it
Adults
Adult dose
Adults: Administer the following doses of calcium dobesilate hydrate orally. 1. Vascular damage and retinopathy: 500~1000mg daily 2. Venous disease: 750mg daily for 1~3 weeks, followed by 500mg daily. Take after meals with plenty of fluids. The dose may be adjusted as appropriate according to age and symptoms.

Ingredients

Manufacturer
Kukje Pharmaceutical Co., Ltd.

Efficacy & effects

Treatment of capillary disorders (e.g., diabetic retinopathy), venous diseases (e.g., edema), and hemorrhoids

  • Increased capillary rupture
  • permeability disorders
  • vascular damage
  • diabetic microangiopathy
  • diabetic retinopathy
  • venous insufficiency
  • post-thrombotic syndrome
  • peripheral venous edema
  • hemorrhoids
View approved original text

This medication is used to improve vascular damage due to increased capillary rupture and permeability disorders, diabetic microangiopathy and diabetic retinopathy, venous insufficiency, post-thrombotic syndrome, peripheral venous edema, and symptoms such as hemorrhoids.

How to take

Adult dose

Adults: Administer the following doses of calcium dobesilate hydrate orally. 1. Vascular damage and retinopathy: 500~1000mg daily 2. Venous disease: 750mg daily for 1~3 weeks, followed by 500mg daily. Take after meals with plenty of fluids. The dose may be adjusted as appropriate according to age and symptoms.

Precautions

This medication contains Dovessilic Acid Calcium Hydrate, and should not be used by some patients. In particular, individuals who are allergic to this medication or its components, pregnant or nursing women, and those with lactose-related genetic issues should not take this medication. Patients with impaired kidney function should use this medication with caution, and especially those with severe renal failure may need to reduce the dosage. Patients with compromised liver function should also use this medication cautiously, and if liver enzyme levels increase, the therapeutic effect and risks should be reassessed. This medication contains sodium bisulfite, which can cause allergic reactions or asthma attacks, so patients with asthma or hypersensitivity to sulfites should be cautious. Some patients may experience side effects such as headache, abdominal pain, nausea, diarrhea, vomiting, joint pain, or muscle pain, and if skin rashes, fever, or blood abnormalities occur, they should stop taking the medication and consult a physician immediately. Rarely, serious blood abnormalities such as agranulocytosis can occur, so if experiencing high fever or infection symptoms, one should visit the hospital immediately. If any hypersensitivity reactions occur, the medication should be stopped immediately and medical assistance sought. This medication does not significantly interact with other drugs but may affect blood test results, so testing and consultation are necessary before use.

Side effects

  • Agranulocytosis
  • neutropenia
  • leukopenia
  • skin rash
  • allergic dermatitis
  • itching
  • urticaria
  • facial edema
  • anaphylactic reaction
  • headache
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  • abdominal pain
  • nausea
  • diarrhea
  • vomiting
  • increased alanine aminotransferase
  • arthralgia
  • myalgia
  • fever
  • chills
  • lethargy
  • fatigue

Not everyone experiences these, and they can vary from person to person.

Storage

This medication is sensitive to light, so it should be stored in an opaque container that blocks light. Additionally, it should be placed in a sealed container that does not allow air to enter, and it is important to maintain a storage temperature between 1 degree and 30 degrees Celsius at room temperature.

Appearance and packaging

Appearance

White oval film-coated tablet

Package unit

30 tablets/bottle, 90 tablets/bottle

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

Questions about this medicine

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For anything that needs medical judgment, consult a doctor or pharmacist.

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.