Memantine Tablets (Memantine Hydrochloride)

Adult dose

This medication is taken orally once a day and should be administered at the same time every day. If necessary, it may be taken twice a day. Dose escalation: The maximum daily dose is 20mg, and to minimize the risk of adverse reactions, the dose should be increased by 5mg weekly for the first 3 weeks. - First week (Day 1-7): 5mg once daily - Second week (Day 8-14): 10mg once daily - Third week (Day 15-21)

This drug should not be used in patients with hypersensitivity to the ingredients, severe liver dysfunction, or severe kidney impairment. It should be administered with caution in patients with epilepsy or a history of seizures, and in patients taking NMDA antagonists. Patients with conditions that may increase urinary pH should be monitored closely, and caution is needed in patients with heart disease or uncontrolled hypertension. While taking this medication, side effects such as dizziness, headache, constipation, drowsiness, and hypertension may occur, so symptoms should be closely monitored. Neuropsychiatric symptoms such as confusion, hallucinations, and seizures have also been reported; immediate consultation with medical personnel should occur if such symptoms arise. Drug interactions may occur when taken with other medications, especially NMDA antagonists, antipsychotics, muscle relaxants, and anticoagulants, so consultation with a specialist is necessary. Pregnant women or nursing mothers must consult a doctor before taking this medication, and women of childbearing potential should be administered cautiously. It is advisable not to use this medicine in children and adolescents under 18 years as safety and efficacy have not been established. In case of overdose, central nervous system symptoms and gastrointestinal symptoms may occur, requiring immediate hospital visit for appropriate treatment. This medication may affect the patient's reaction speed and concentration, so special care should be taken when driving or operating machinery. Finally, keep this product out of reach of children and avoid transferring the drugs to another container.

Serious side effects

Seizure

Mild side effects

• Dizziness
• headache
• constipation
• drowsiness
• hypertension
• confusion
• hallucination
• psychiatric reactions
• balance disorder
• gait abnormalities

This drug is sensitive to air and moisture; therefore, it must be stored in a tightly sealed container. Additionally, it is preferable to avoid direct sunlight and store at room temperature between 1°C and 30°C.

Appearance

White elongated film-coated tablet

Package unit

30 tablets/bottle, 100 tablets/bottle