Lipimet 160 mg (Fenofibrate)

Adult dose

Fenofibrate: Take 160 mg orally once a day immediately after meals. Fenofibrate must be administered in conjunction with dietary therapy. This medication may have reduced absorption when taken on an empty stomach, so it should be taken immediately after meals.

Child dose

There are no clinical data regarding the use of this medication in children.

This medication should not be used in patients with poor liver function. If liver function is impaired, the medication can be harmful to the body. Patients with moderate to severe renal impairment should also avoid this medication. Severe renal impairment may lead to rhabdomyolysis, which can damage muscle tissue. Women who are pregnant or may become pregnant, and breastfeeding women should not take this medication because it can be harmful to the fetus or baby. Patients with an allergic reaction to this medication or its components should also avoid using it. Patients with gallbladder issues or a history of gallstone formation need to be cautious, as this medication may lead to further gallstone formation. Patients who have experienced photosensitivity while taking fibrate class medications or ketoprofen should exercise caution with this medication as well. Children should not take this medication. Patients with biliary cirrhosis or pancreatitis should also avoid using this medication, except in cases where pancreatitis is due to severe hypertriglyceridemia. Patients with lactose intolerance or certain genetic metabolic disorders should not take this medication due to the lactose it contains. Patients with mild renal impairment or a history of such should be cautious, as there is a risk of rhabdomyolysis, and they may need to reduce the dosage or increase the dosing interval. Patients with abnormal liver function tests or a history should also be cautious due to the risk of worsening liver function. Patients with hypoalbuminemia, a history of gallstones, those taking anticoagulants, and the elderly should use this medication with caution. This medication can affect the liver and biliary tract, leading to elevated liver enzyme levels, gallstones, and cholestatic hepatitis as side effects. Skin reactions such as rash, itching, and photosensitivity may occur; hair loss can occur rarely. Neurological symptoms such as dizziness, headache, and weakness may manifest. There may be a risk of vascular issues, such as thromboembolism, thus caution is needed. Musculoskeletal reactions such as muscle pain, cramps, and elevated creatine kinase levels may occur, and in severe cases, rhabdomyolysis may develop, so consult a doctor immediately if symptoms appear. Gastrointestinal side effects such as abdominal pain, nausea, vomiting, diarrhea, and abdominal distension may frequently occur, and pancreatitis may occur rarely. Pulmonary complications, decreased blood cells, and renal function abnormalities have also been reported, hence regular check-ups are necessary. This medication may interact with other drugs, so especially discuss with your doctor when taking it with statins, anticoagulants, antidiabetic agents, urate-lowering agents, and oral contraceptives. This medication should not be taken during pregnancy as it may harm the fetus, and it is advisable to avoid it while breastfeeding. Elderly patients should exercise caution as liver and renal functions may be weakened, increasing the risk of adverse reactions, and serum creatinine levels should be checked regularly. There is no specific antidote for overdose, and it cannot be removed by hemodialysis, so strict adherence to the dosage is necessary. This medication should be kept out of the reach of children, and transferring it to another container is not advisable for quality maintenance.

Serious side effects

• Hives, severe swelling (angioedema), chest tightness, difficulty breathing, cold sweat, pallor, severe allergic reactions.
• Severe rash accompanied by high fever, blisters, skin peeling, painful mucous membranes of the mouth/eyes, severe skin reactions.
• Shortness of breath or difficulty breathing, asthma attacks, respiratory issues accompanied by cough and fever.
• Yellowing of the skin or eyes (jaundice), severe lethargy, liver issues (jaundice).
• Sudden and very severe reactions.

Mild side effects

Elevated serum aminotransferase levels, liver enlargement, cholestatic hepatitis, gallstones, rash, itching, photosensitivity, hair loss, weakness, fever, dizziness, headache, peripheral neuropathy, thromboembolism, elevated creatine kinase (CK), muscle pain, muscle cramps, joint pain, gastrointestinal disturbances (abdominal pain, nausea, vomiting, diarrhea, abdominal distension), pulmonary complications, hemoglobin decrease, leukopenia, eosinophilia, elevated serum creatinine and urea

This medication may be sensitive to air or moisture, so it must be stored in a tightly sealed container. Additionally, it is best to store the medication at room temperature between 1 to 30 degrees Celsius. Proper storage helps maintain the medication's effectiveness for a longer period.

Appearance

White oblong film-coated tablet

Package unit

100 tablets (10 tablets/PTP) x 10