Medication info
Nocdernasal Sublingual Tablet 50 Micrograms (Desmopressin Acetate)

Nocdernasal Sublingual Tablet 50 Micrograms (Desmopressin Acetate)

Prescription medicationSublingual Tablet
Ingredient · strength
Desmopressin Acetate›0.057mg / 1 tablet
Manufacturer / importer
Ferring Pharmaceuticals Korea Co., Ltd.
Appearance
White round sublingual tablet
Packaging
30 tablets (10 tablets PTP packaging × 3)/box
Approval status
Active

MFDS item code 201707571 · Approved 2017.10.24 · Insurance code 652500400

Summary

Main use
Treatment of nocturia due to idiopathic nocturnal polyuria in adults
Who uses it
Adults
Adult dosage
Men: Administer 50 micrograms sublingually once daily, 1 hour before bedtime, without water. Women: Administer 25 micrograms sublingually once daily, 1 hour before bedtime, without water. Dose escalation of desmopressin is not recommended in elderly patients aged 65 years or older. If this medicine does not produce a sufficient response in patients under 65 years of age, the dose may be increased using another oral desmopressin preparation.

Ingredients

Importer
Ferring Pharmaceuticals Korea Co., Ltd.

Efficacy & effects

Treatment of nocturia due to idiopathic nocturnal polyuria in adults

  • Idiopathic nocturia
  • nocturia symptoms
View approved original text

This medication is used to treat nocturia symptoms caused by idiopathic nocturia in adults. It alleviates the symptom of frequently urinating at night, improving sleep quality and aiding uninterrupted deep sleep. This helps reduce discomfort in daily life and improves overall quality of life.

Dosage and Administration

Adult dosage

Men: Administer 50 micrograms sublingually once daily, 1 hour before bedtime, without water. Women: Administer 25 micrograms sublingually once daily, 1 hour before bedtime, without water. Dose escalation of desmopressin is not recommended in elderly patients aged 65 years or older. If this medicine does not produce a sufficient response in patients under 65 years of age, the dose may be increased using another oral desmopressin preparation.

Precautions

This medication helps regulate the body's fluid balance. When taking this medication, fluid intake must be controlled. Excessive fluid intake can lower serum sodium levels, leading to hyponatremia or water intoxication, so it is important to drink water only when thirsty. Particularly, elderly patients or those with certain conditions are at higher risk for serious side effects such as hyponatremia, so caution is required. Patients who are hypersensitive to this drug or have heart failure, severe renal failure, hyponatremia, Syndrome of inappropriate antidiuretic hormone secretion, or nephrogenic diabetes insipidus should not take this medication. Women who are pregnant or may become pregnant, patients with hypertension, cardiovascular disease, or those at risk for electrolyte imbalance should also use this medication with caution. While taking this medication, side effects such as headache, dizziness, dry mouth, and hyponatremia may occur, so if symptoms are severe, consult medical personnel immediately. Fluid intake should be restricted from 1 hour before until 8 hours after taking the medication, and serum sodium levels should be regularly monitored; if abnormalities occur, the use of the medication should be discontinued. Additionally, the risk of hyponatremia may increase when used in combination with certain medications, so if other medications are being taken, this must be disclosed to healthcare professionals. Pregnant or nursing women should also be cautious when using this medication, and its use in children is not recommended. In case of overdose, the risk of fluid retention and hyponatremia increases, so immediate medical assistance should be sought, and it is safe to store the medication out of reach of children and in its original container.

Side effects

  • Dry mouth
  • headache
  • hyponatremia
  • dizziness
  • nausea
  • vomiting
  • decreased serum sodium
  • weight gain
  • fatigue
  • abdominal pain
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  • muscle cramps
  • confusion
  • decreased perception
  • seizures
  • coma
  • diarrhea
  • constipation
  • abdominal bloating
  • tiredness
  • peripheral edema
  • anaphylaxis

Not everyone experiences these, and they can vary from person to person.

Storage

This medication must be stored in a tightly sealed container to prevent air or moisture from entering. The storage temperature should be maintained at room temperature between 1 and 30 degrees Celsius. This helps preserve the medication's effectiveness and safety for a long time.

Appearance and packaging

Appearance

White round sublingual tablet

Package unit

30 tablets (10 tablets PTP packaging × 3)/box

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.