Evistra Plus Tablet

Adult dose

Once daily, 1 tablet orally.

This medication should be used with caution in patients at risk of thromboembolism, especially if there is a condition that limits mobility, the use of the medication should be discontinued. This drug is not recommended for patients with impaired liver function, and liver function tests should be monitored regularly. It should not be used in premenopausal women as safety has not been established. It is advisable not to use this medication for cardiovascular protection in postmenopausal women with cardiovascular disease or those at high risk. Co-administration with systemic estrogen is not recommended. Women who are pregnant or may become pregnant, and nursing mothers should not take this medication. Patients with a history of thromboembolism, liver disorders, uterine bleeding, endometrial cancer symptoms, and patients with prolonged immobility should not use this medication. Patients with specific genetic metabolic disorders should also avoid this medication. Patients with high blood triglycerides or impaired kidney function, and those with a history of kidney stones should be careful when using this drug. During treatment, side effects such as leg cramps, facial flushing, cold symptoms, peripheral edema may occur; if symptoms are severe, consult a doctor immediately. It is advisable to take supplements if calcium intake is insufficient, and additional vitamin D supplementation may be needed for patients at high risk of vitamin D deficiency. While this medication has minimal specific interactions with other drugs, caution is necessary with certain medications, so inform your doctor of any concurrent medications. As it may harm the fetus during pregnancy, women who are pregnant or planning to become pregnant should avoid taking it, and nursing mothers should also refrain from use for safety. Safety and efficacy in children have not been established; hence it should not be used in pediatric patients. It can be safely used in the elderly, but vitamin D intake should be adjusted for the elderly. In case of overdose, appropriate treatment according to symptoms is necessary, and there is no specific antidote. Store out of reach of children, and it is advisable not to transfer to other containers.

Serious side effects

Deep vein thrombosis, pulmonary embolism, retinal vein thrombosis, superficial venous thrombophlebitis, stroke, death related to venous thromboembolism (VTE), urticaria, severe swelling (edema), chest tightness, difficulty breathing, cold sweats, pallor, severe rash with high fever, blisters, skin peeling, pain in oral/ocular mucosa, shortness of breath or difficulty breathing, asthma attacks, cough with fever accompanied respiratory abnormalities, yellowing of skin or eyes.

Mild side effects

Vasodilation (facial flushing), leg cramps, cold symptoms, peripheral edema, reduced platelet count, nausea, vomiting, abdominal pain, dyspepsia, elevated blood pressure, headache, rash, breast symptoms (pain, swelling, tenderness), facial edema, heartburn, constipation, itching, palpitations, fever, weakness, sweating, myalgia, insomnia, perineal pain, weight gain, arthritis, rheumatological symptoms, pain, fatigue, tightness, discomfort in the chest and breast area, skin lesions, anxiety, weight.

This medication should be stored in a tightly closed container to avoid exposure to air and moisture. It is best to maintain storage temperatures between 1 degree and 30 degrees Celsius.

Appearance

Yellow round film-coated tablet

Package unit

30 tablets (10 tablets/PTP X 3)