Medication info
Dobesel Tablets 500 mg (Dobesilic Acid Calcium Hydrate)

Dobesel Tablets 500 mg (Dobesilic Acid Calcium Hydrate)

Prescription medicationTabletOral
Ingredient · strength
Dobesilate Calcium Hydrate›500mg / 1 tablet
Manufacturer / importer
Aju Pharmaceutical Co., Ltd.
Appearance
White oblong tablet
Packaging
30 tablets/bottle, 90 tablets/bottle
Approval status
Active

MFDS item code 201707248 · Approved 2017.09.27 · Insurance code 654004930

Summary

Main use
Treatment of capillary disorders (such as diabetic retinopathy), venous disorders (such as edema), and hemorrhoids
Who takes it
Adults
Adult dose
Adults: Administer the following doses of calcium dobesilate hydrate orally. 1. Vascular damage and retinopathy: 500~1000mg daily 2. Venous disorders: Administer 750mg daily for 1~3 weeks, then 500mg daily thereafter. Administer after meals with plenty of fluids. Adjust the dose as appropriate according to age and symptoms.

Ingredients

Manufacturer
Aju Pharmaceutical Co., Ltd.

Efficacy & effects

Treatment of capillary disorders (such as diabetic retinopathy), venous disorders (such as edema), and hemorrhoids

  • Capillary rupture
  • permeability disorder
  • vascular damage
  • diabetic microvascular disorders
  • diabetic retinopathy
  • venous insufficiency
  • post-thrombotic syndrome
  • peripheral congestive edema
  • hemorrhoids
View approved original text

This medication is used for vascular damage accompanied by increased capillary rupture and permeability disorders, diabetic microvascular disorders, diabetic retinopathy, venous insufficiency, post-thrombotic syndrome, peripheral congestive edema, and symptoms such as hemorrhoids.

How to take

Adult dose

Adults: Administer the following doses of calcium dobesilate hydrate orally. 1. Vascular damage and retinopathy: 500~1000mg daily 2. Venous disorders: Administer 750mg daily for 1~3 weeks, then 500mg daily thereafter. Administer after meals with plenty of fluids. Adjust the dose as appropriate according to age and symptoms.

Precautions

This medication contains Dobesilic Acid Calcium Hydrate as its active ingredient and should not be used by certain patients. First, individuals allergic to this medication or its components should not take it. Additionally, pregnant or nursing women should not use this medication. Since this medication contains lactose, individuals with lactose intolerance or specific genetic metabolic disorders should avoid taking it. Its safety and efficacy have not been fully verified for patients with impaired renal function, so it should be used with caution, and in particular, the dosage may need to be reduced in patients with severe renal failure. Patients with impaired liver function also need to use this medication carefully, and if there is an increase in liver enzyme levels, treatment should be reassessed. This medication contains sulfite, which may cause allergic reactions or severe asthma attacks in some sensitive individuals, especially asthmatics. Common side effects during treatment may include headaches, abdominal pain, nausea, diarrhea, vomiting, joint pain, and muscle pain. Allergic reactions such as skin rash, itching, urticaria, and facial swelling may occur rarely, and in severe cases, life-threatening reactions such as anaphylaxis may occur. If symptoms of infection such as high fever, sore throat, or oral infections develop during treatment, notify a doctor immediately, and check the condition through blood tests and discontinue medication if necessary. If hypersensitivity is suspected, stop the medication immediately and consult a healthcare professional. There are no known interactions with other medications, but since it may affect blood test results, inform the healthcare professional about this before undergoing tests.

Side effects

  • Agranulocytosis
  • neutropenia
  • leukopenia
  • hypersensitivity reactions
  • skin rash
  • allergic dermatitis
  • itching
  • urticaria
  • facial swelling
  • anaphylaxis
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  • headache
  • abdominal pain
  • nausea
  • diarrhea
  • vomiting
  • increased alanine aminotransferase
  • arthralgia
  • myalgia
  • fever
  • chills
  • lethargy
  • fatigue

Not everyone experiences these, and they can vary from person to person.

Storage

This medication is sensitive to light and should be stored in a container that does not allow light to enter. Additionally, it is best stored at room temperature between 1°C and 30°C. Proper storage will help maintain the medication's effectiveness.

Appearance and packaging

Appearance

White oblong tablet

Package unit

30 tablets/bottle, 90 tablets/bottle

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

Questions about this medicine

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For anything that needs medical judgment, consult a doctor or pharmacist.

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.