Medication info
S-Amlodipine Tablets 2.5 mg (S-Amlodipine Besylate 2.5 Hydrate)

S-Amlodipine Tablets 2.5 mg (S-Amlodipine Besylate 2.5 Hydrate)

Prescription medicationTablet경구
Ingredient · strength
S-Amlodipine Besylate 2.5 Hydrate›3.74mg / 1 tablet
Manufacturer / importer
(주)일화
Appearance
A light yellow heart-shaped tablet with a scored line.
Packaging
30 tablets/bottle, 300 tablets/bottle
Approval status
Active

MFDS item code 201707244 · Approved 2017.09.27 · Insurance code 640903490

Summary

Main use
Treatment of myocardial ischemia caused by hypertension and coronary artery disease (stable angina, variant angina).
Who takes it
Adults
Adult dose
Administer 2.5 mg orally once daily as S-amlo dipine, and may be increased to a maximum of 5 mg daily depending on the patient's response. This medication should be taken with a sufficient amount of water.

Ingredients

Manufacturer
(주)일화

Efficacy & effects

Treatment of myocardial ischemia caused by hypertension and coronary artery disease (stable angina, variant angina).

  • Hypertension
  • fixed occlusion of coronary arteries
  • vasoconstriction of coronary arteries
  • myocardial ischemia.
View approved original text

This medication is used for myocardial ischemia such as stable angina caused by hypertension and fixed coronary artery occlusion, as well as variant angina due to vasoconstriction of the coronary arteries.

How to take

Adult dose

Administer 2.5 mg orally once daily as S-amlo dipine, and may be increased to a maximum of 5 mg daily depending on the patient's response. This medication should be taken with a sufficient amount of water.

Precautions

This medicine should not be used in certain patients. For example, patients allergic to this drug or similar components, pregnant women or those who may become pregnant, nursing women, patients in shock, those with severe aortic stenosis, unstable angina patients, patients who have recently experienced a myocardial infarction, patients with severe liver function impairment, and those with severe hypotension should not be administered this medication. Additionally, caution should be exercised with patients with very poor kidney function, the elderly, patients with acute heart failure, patients with rapidly increasing blood pressure, and patients with mild to moderate liver function impairment. This drug can have side effects, with the most common being flushing accompanied by warmth, fatigue, swelling, palpitations, dizziness, headache, abdominal pain, nausea, drowsiness, and ankle edema. Rarely, symptoms such as dry mouth or excessive sweating, a heavy or lethargic feeling, blood pressure drop, dizziness due to orthostatic hypotension, vasculitis, syncope, insomnia, depression, skin rash, and liver function abnormalities may occur, so if these symptoms arise, immediate consultation with a medical professional is advised. Abruptly stopping this medication can worsen symptoms; therefore, dosage should not be stopped without a doctor's instruction and should be gradually reduced. Patients with weakened liver or heart function should take special care when using this medication, and since this drug lowers blood pressure slowly, it is not suitable for emergency situations. When taking this medication, it should be consumed with plenty of water, and caution should be exercised while driving or operating machinery as dizziness or drowsiness may occur. Interactions with other medications may occur, so if taking other drugs, you must inform your doctor or pharmacist, and taking it with grapefruit juice is not recommended. It is generally safe to avoid using this medication during pregnancy or breastfeeding, and its use is recommended only for patients aged six and older. In case of overdose, severe hypotension, cardiac abnormalities, and coma may occur, and immediate emergency treatment is required, while hemodialysis is not effective. Finally, this medication should be kept out of reach of children and should not be transferred to another container.

Side effects and when to seek care immediately

Serious side effects

Hives, severe swelling (edema), angioedema, toxic epidermal necrolysis, Stevens-Johnson syndrome, clinical symptoms of liver dysfunction (weakness, anorexia, persistent nausea), jaundice, paralysis, coma, hypotension, shock, myocardial infarction, arrhythmia, heart block.

Mild side effects

  • Flushing with warmth
  • fatigue
  • swelling
  • palpitations
  • dizziness
  • headache
  • migraine
  • weakness
  • abdominal pain
  • nausea
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  • indigestion
  • drowsiness
  • dry mouth
  • increased sweating
  • weakness
  • lethargy
  • pain
  • weight changes
  • chills
  • hypotension
  • orthostatic hypotension
  • positional dizziness
  • peripheral ischemia
  • vasculitis
  • syncope
  • tachycardia
  • peripheral edema
  • tension
  • sensory loss/abnormal sensation
  • peripheral neuropathy
  • altered taste
  • tremors
  • extrapyramidal disorders
  • erectile dysfunction
  • gynecomastia

Not everyone experiences these, and they can vary from person to person.

Storage

This medication should be stored in a tightly sealed container to protect from air and moisture exposure. Also, it is recommended to store the medication at room temperature between 1°C and 30°C. This helps maintain the drug's effectiveness for a long time.

Appearance and packaging

Appearance

A light yellow heart-shaped tablet with a scored line.

Package unit

30 tablets/bottle, 300 tablets/bottle

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

Questions about this medicine

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For anything that needs medical judgment, consult a doctor or pharmacist.

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.