Medication info

Genewon Zinc Injection (Zinc Sulfate Heptahydrate)

Prescription medicationInjections
Ingredient · strength
Zinc Sulfate Hydrate›4.4mg / 1mL
Manufacturer / importer
주식회사제뉴원사이언스
Appearance
A colorless, odorless, transparent liquid contained in a colorless, transparent vial injection.
Packaging
10mL×10 vials
Approval status
Active

MFDS item code 201707112 · Notified 2017.09.18

Summary

Main use
Improving nutritional status through zinc supplementation
Who uses it
Adults · Children
Adult dosage
Use as prescribed by a physician, adjusting the dosage according to plasma trace element levels. Metabolically stable TPN patients: 2.5 to 4 mg/day Adult patients with fluid loss from the intestine: an additional 12.2 mg/L (loss of fluid) or an additional 17.1 mg/kg (amount excreted) Acute burn condition: 4.5 to 6 mg/day
Children's dosage
Children under 5 years: 100 µg/kg/day Premature infants weighing 3 kg or less: 300 µg/kg/day

Ingredients

Manufacturer
주식회사제뉴원사이언스

Efficacy & effects

Improving nutritional status through zinc supplementation

View approved original text

Patients receiving Total Parenteral Nutrition (TPN) may become deficient in zinc, necessitating zinc supplementation. Zinc is an essential mineral important for maintaining immune function and skin health, and deficiency can lead to delayed wound healing or decreased immunity. Therefore, appropriate zinc supplementation during TPN helps to prevent these issues and aids in patient recovery.

Dosage and Administration

Adult dosage

Use as prescribed by a physician, adjusting the dosage according to plasma trace element levels. Metabolically stable TPN patients: 2.5 to 4 mg/day Adult patients with fluid loss from the intestine: an additional 12.2 mg/L (loss of fluid) or an additional 17.1 mg/kg (amount excreted) Acute burn condition: 4.5 to 6 mg/day

Children's dosage

Children under 5 years: 100 µg/kg/day Premature infants weighing 3 kg or less: 300 µg/kg/day

Precautions

This medication should not be injected directly into the peripheral vein without dilution. Injecting directly into the peripheral vein may cause phlebitis or can lead to rapid intravenous administration causing damage to the kidneys. The amount of zinc in this medication is very small, so toxic symptoms are unlikely to occur. When mixing this medication with TPN solutions, it is recommended to work in a cleanroom environment to maintain sterility. For non-oral medications, it is important to visually check for any precipitation or discoloration before administration. Administering zinc together with copper may reduce the plasma copper concentration, so the concentrations of both elements should be measured at regular intervals and taken into account for the next dosing. This medication is eliminated through the small intestine and kidneys, so patients with abnormalities in these excretory organs should consider the possibility of zinc accumulation in the body. When administering this medication to pregnant women or women of childbearing potential, it should only be used when the benefits outweigh the risks. Since zinc can cross the placenta and may be present in breast milk, pregnant and nursing mothers should use it cautiously. In cases of overdose, symptoms may include nausea, vomiting, dehydration, electrolyte imbalance, dizziness, abdominal pain, drowsiness, and ataxia, which can be severe and potentially fatal. Calcium supplementation may help to prevent toxic symptoms of zinc. This medication should be stored out of reach of children and kept in its original packaging in a dry place at room temperature. Since it does not contain preservatives, any unused portions must be discarded.

Side effects and when to seek care immediately

Mild side effects

  • Nausea
  • vomiting
  • dehydration
  • electrolyte imbalance
  • dizziness
  • abdominal pain
  • drowsiness
  • ataxia

Not everyone experiences these, and they can vary from person to person.

Storage

This medication should be stored in a sealed container to prevent air or moisture ingress, and it is best to keep it at a temperature between 1 to 30 degrees Celsius at room temperature. This helps maintain the effectiveness of the medication over time.

Appearance and packaging

Appearance

A colorless, odorless, transparent liquid contained in a colorless, transparent vial injection.

Package unit

10mL×10 vials

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.