Twinon 40/10 mg Tablets

Adult dose

The recommended dosage is one tablet once daily, taken with water regardless of meals. It is advised to take it at the same time each day (e.g., in the morning). There are dosage adjustment guidelines for patients with kidney impairment, liver impairment, and the elderly; patients with severe kidney impairment should start treatment at a lower dose and gradually increase. The elderly should start at a lower dose and increase gradually.

Child dose

Safety and efficacy in pediatric patients under 18 years of age have not been established, therefore its use is not recommended.

This medication should not be used during pregnancy, especially in the second and third trimesters, as it can cause serious harm to the fetus. It should not be administered to patients with allergies to its active ingredients, liver impairment, severe hypotension, or certain specific heart conditions. Patients with impaired liver function, gastrointestinal disorders, kidney issues, and the elderly should exercise caution when using this medication. Common side effects may include dizziness or swelling, and in rare cases, serious side effects may occur. Women planning to become pregnant or currently pregnant should not take this medication, and it should be discontinued immediately if pregnancy is confirmed. Patients with low blood pressure or impaired kidney function should consult a doctor before taking this medication and should regularly monitor their blood pressure and kidney functions during treatment. This medication may interact when taken with other antihypertensive medications or specific drugs, so it is crucial to inform the healthcare provider about any other medications being taken. Breastfeeding women are advised not to take this medication, and it is not recommended for children or adolescents under 18 years old. In case of overdose, severe hypotension, dizziness, or heart problems may occur; therefore, the dosage should be strictly adhered to, and if any unusual symptoms occur, immediate medical attention should be sought. This medication should be stored out of reach of children, in a dark, airtight container, and should be taken immediately after opening for safety.

Serious side effects

Hives, severe swelling (angioedema), chest tightness, difficulty breathing, cold sweat, pallor (severe allergic reaction), severe rash with high fever, blisters, peeling skin, pain in oral/ocular mucosa (severe skin adverse reactions), wheezing or difficulty breathing, asthma attack, respiratory abnormalities with cough and fever, yellowing of the skin or eyes (jaundice), extreme lethargy (liver dysfunction), sudden and very severe headache.

Mild side effects

• Dizziness
• peripheral edema
• upper respiratory infection
• urinary tract infection
• anemia
• hyperkalemia
• hypoglycemia
• hyponatremia
• hyperglycemia
• depression

This medication may be sensitive to light and should be stored in a light-resistant, sealed container. It is important to maintain a storage temperature between 1 to 30 degrees Celsius. This will help preserve the effectiveness of the medication.

Appearance

For domestic use: white or whitish rectangular tablets For export: oval double-coated tablets with white and light gray on both sides.

Package unit

30 tablets/box [(10 tablets/Alu-Alu*3)], 30 tablets/bottle