Medication info
Sinjiroxine Tablet 88 Micrograms (Sodium Levothyroxine Hydrate)

Sinjiroxine Tablet 88 Micrograms (Sodium Levothyroxine Hydrate)

Prescription medicationTabletOral
Ingredient · strength
Levothyroxine Sodium Hydrate›0.088mg / 1 tablet
Manufacturer / importer
Darim Biotech Co., Ltd.
Appearance
Orange oval tablet
Packaging
100 tablets/bottle, 300 tablets/bottle
Approval status
Active

MFDS item code 201706861 · Approved 2017.08.29 · Insurance code 664602250

Summary

Main use
Treatment of hypothyroidism, myxedema, and cretinism
Who takes it
Adults
Adult dose
Adults: The usual dose is 25-400㎍ of levothyroxine sodium orally once daily. The usual initial dose is 25-100㎍, and the maintenance dose is 100-400㎍. Adjust the dose as appropriate according to age and symptoms.

Ingredients

Manufacturer
Darim Biotech Co., Ltd.

Efficacy & effects

Treatment of hypothyroidism, myxedema, and cretinism

  • Hypothyroidism
  • myxedema
  • cretinism
View approved original text

Used for diseases caused by hypothyroidism, such as myxedema and cretinism.

How to take

Adult dose

Adults: The usual dose is 25-400㎍ of levothyroxine sodium orally once daily. The usual initial dose is 25-100㎍, and the maintenance dose is 100-400㎍. Adjust the dose as appropriate according to age and symptoms.

Precautions

This medication is not appropriate for individuals with normal thyroid function who take it for weight loss purposes. Particularly, serious side effects may occur if taken with sympathomimetic amines. It should not be administered to patients with acute heart disease, hyperthyroidism, or adrenal insufficiency. Additionally, patients allergic to this medication or with genetic issues, such as lactose intolerance, should not take it. Patients with hypertension, angina, diabetes, or adrenal cortical insufficiency should take this medication with caution, and it's essential to gradually increase the dosage, maintaining the minimum dose. Overdose may result in various side effects, such as cardiac arrhythmia, insomnia, nervousness, vomiting, diarrhea, and myalgia; if these symptoms occur, use should be discontinued immediately and medical consultation sought. This medication can cause liver dysfunction, hence appropriate action should be taken if liver dysfunction symptoms occur. Patients with hypothyroidism should start with a small amount and gradually increase the dosage, and diabetic patients should closely monitor their blood sugar levels while adjusting insulin or hypoglycemic agent dosages. Patients with cardiovascular disease should reduce their dosage or adjust administration if chest pain or symptom worsening occurs. It is advisable not to stop treatment during pregnancy, and caution should be taken during breastfeeding as well. Pediatric patients should be diagnosed early and treated adequately, as overtreatment may negatively affect growth. Elderly individuals should start at a lower dose due to reduced body function and gradually increase the dose. This medication may interact with other drugs, so any concomitant medications should be disclosed to a healthcare provider. In cases of overdose, inducing vomiting and gastric lavage may reduce drug absorption, and beta-blockers may be used to control symptoms if necessary. During thyroid function testing while taking this medication, it is advisable to temporarily discontinue any supplements containing biotin.

Side effects

  • Palpitations
  • increased heart rate
  • arrhythmia
  • angina
  • elevated pulse pressure
  • tremors
  • insomnia
  • headache
  • dizziness
  • sweating
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  • nervousness
  • excitement
  • anxiety
  • mania
  • mental disorders
  • convulsions
  • loss of appetite
  • vomiting
  • diarrhea
  • abdominal cramps
  • myalgia
  • menstrual disorders
  • weight loss
  • lethargy
  • hyperhidrosis
  • flushing of the skin
  • rash
  • liver dysfunction
  • fever
  • fatigue
  • mydriasis
  • hypercalciuria
  • paroxysmal increase in appetite
  • shock
  • congestive heart failure

Not everyone experiences these, and they can vary from person to person.

Storage

This medication is sensitive to light, so it should be stored in a container that does not allow light in. Additionally, it is important to store it at room temperature between 1 to 25 degrees Celsius to maintain its effectiveness.

Appearance and packaging

Appearance

Orange oval tablet

Package unit

100 tablets/bottle, 300 tablets/bottle

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

Questions about this medicine

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For anything that needs medical judgment, consult a doctor or pharmacist.

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.