Imagimed MR Sustained-release Tablet 35mg (Trimetazidine Hydrochloride)

Adult dosage

Adults: Take 35mg twice daily, with breakfast and dinner. Patients with renal impairment: Patients with moderate renal impairment (creatinine clearance 30-60 ml/min) should take 35mg once daily with breakfast.

This medication is not intended for use in cases where angina suddenly worsens, and it should not be used on the first day or prior to hospitalization if there are serious heart issues. If angina symptoms occur, the patient must have their condition reassessed at a hospital and an appropriate treatment method must be determined. People allergic to this medication or its components should not take it. Additionally, individuals with movement disorders such as Parkinson's disease, tremors, or restless leg syndrome should not take this medication. Patients with severely impaired kidney function may also be at risk when using this medication and should avoid it. Those with moderately reduced kidney function or elderly patients over 75 years of age should take extra caution when using this medication. Dizziness or headaches are common symptoms when taking this medication. Rarely, symptoms such as a rapid heartbeat or low blood pressure may occur, and gastrointestinal disturbances, skin rashes, or itching may also be present. This medication can worsen symptoms of Parkinson's disease; therefore, elderly patients should undergo regular examination by a neurologist. If movement disorder symptoms occur, the patient should immediately discontinue the medication and consult a physician. Most symptoms recover after stopping the medication, but if symptoms persist for more than 4 months, specialist care is required. It may not be safe to take this medication during pregnancy, so it is advisable to avoid taking it if possible. It is also recommended not to use this medication during breastfeeding, as it is uncertain whether this drug passes into breast milk. The safety and efficacy of this medication in children under the age of 18 have not been established, so it is not recommended. Elderly patients with reduced kidney function may retain the medication in their bodies longer, so doses may need to be adjusted. If this medication is overdosed, there is no specific antidote, and symptomatic treatment should be provided. Dizziness or drowsiness may occur during use, so caution should be taken when driving or operating machinery. This medication should be kept out of reach of children, and expired medications should not be taken.

dizziness, headache, symptoms of Parkinson's disease (tremors, akinesia, rigidity), gait instability, restless legs syndrome, other movement-related disorders, sleep disorders (insomnia, drowsiness), palpitations, premature contractions, tachycardia, arterial hypotension, anxiety, drowsiness, orthostatic hypotension associated with falls, flushing, abdominal pain, diarrhea, dyspepsia, nausea, vomiting, constipation, rash, itching, urticaria, acute generalized exanthematous pustulosis (AGEP), angioedema, asthenia, agranulocytosis, thrombocytopenia, thrombocytopenic purpura, hepatitis

This medication should be stored in a tightly closed container that is air-tight, and it is best kept at room temperature between 1°C and 30°C. Storing it this way helps maintain the medicine's effectiveness for a longer period.

Appearance

Brownish-pink, double convex, round sustained-release film-coated tablet

Package unit

100 tablets (10 tablets/PTP × 10)