Selperin Tablet 10 mg (Solifenacin Succinate)

Adult dose

The usual recommended dose for adults (including elderly patients) is 5mg once daily. If necessary, the dose may be increased to a maximum of 10mg once daily. This medicine may be taken with or without food and should be swallowed whole with water. Dosage adjustment is required for the following patients. 1. Patients with renal impairment: No dose adjustment is necessary in patients with mild or moderate renal impairment (creatinine clearance>30ml/min). Use with caution in patients with severe renal impairment (creatinine clearance≤30ml/min), and do not exceed 5mg once daily. 2. Patients with hepatic impairment: No dose adjustment is necessary in patients with mild hepatic impairment. Use with caution in patients with moderate hepatic impairment (Child-Pugh class B), and do not exceed 5mg once daily. 3. Patients receiving potent cytochrome P450 3A4 (CYP3A4) inhibitors: In patients receiving ketoconazole or other potent CYP3A4 inhibitors (e.g., ritonavir, nelfinavir, itraconazole), limit the maximum daily dose to 5mg.

This drug should not be used in patients with urinary retention, severe gastrointestinal disease, myasthenia gravis, or angle-closure glaucoma. Additionally, it should not be administered to those with hypersensitivity to this drug or its ingredients, patients undergoing dialysis, or patients with severe liver or kidney impairment. Caution is advised for patients at risk of urinary retention or those with gastrointestinal obstructive diseases, or those at risk of decreased gastrointestinal motility. Patients with severe kidney impairment or moderate liver impairment should have their dosage limited, and caution is required when combined with certain potent drugs. Use of this medication may cause side effects such as dry mouth, constipation, blurred vision, urinary retention, and dry eyes. Particularly, serious side effects such as gastrointestinal obstruction may occur with high-dose administration, so caution is required. This medication can affect driving or operating machinery, requiring caution. If serious allergic reactions such as angioedema or anaphylaxis occur, administration should be stopped immediately and treatment sought. This drug is metabolized by specific enzymes, so interactions may occur when used with enzyme inhibitors or inducers. Women who are pregnant or breastfeeding should use this drug with caution, and safety in pediatrics has not been established, so it should not be used in children. In case of overdose, appropriate treatment and professional care according to symptoms are necessary. Consult with a physician before taking this medication and inform them of your health status and any other medications you are taking.

• dry mouth
• constipation
• blurred vision
• urinary retention
• dry eyes
• nausea
• dyspepsia
• upper abdominal pain
• vomiting
• urinary tract infection

This drug should be stored in a tightly closed container to prevent air or moisture from entering, and it is best kept at room temperature between 1 degree and 30 degrees Celsius. Storing it this way will maintain the drug's effectiveness and prevent deterioration.

Appearance

Bright pink round film-coated tablet

Package unit

100 tablets (10 tablets/PTP X 10)