Two Tops Plus Tablets 40/5/12.5 Milligrams

Adult dose

The recommended dosage for this medication is one tablet once a day, taken with water regardless of meals. It is advisable to take it at the same time each day (e.g., in the morning). Administer this medication 40/5/12.5 milligrams to patients whose blood pressure is not controlled with the combination therapy of telmisartan and amlodipine, and adjust the dosage at intervals of more than 2 weeks considering the patient's blood pressure response. The maximum recommended dose of this medication is 80/10/25 milligrams.

This medication can cause serious harm to the fetus, particularly during the second and third trimesters, so women who are pregnant or may become pregnant should not take it. If pregnancy is confirmed, the use of this medication should be discontinued as soon as possible. Patients with allergies to this medication or its components, or those with specific liver disorders, kidney disorders, heart disease, hypotension, etc., should avoid taking it. Additionally, it is advisable that women who are breastfeeding do not use this medication. Patients with specific heart valve diseases, liver diseases, renovascular hypertension, elderly individuals, and diabetic patients should use this medication cautiously and require regular monitoring by a physician. Common side effects may include dizziness, headache, edema, and nausea, and in rare cases, serious adverse reactions may occur. If symptoms persist or worsen, consult a doctor immediately. Symptoms of hypotension may arise due to excessively low blood pressure, so patients should be laid down if such symptoms occur and should seek appropriate medical treatment if necessary. This medication may interact with other antihypertensive medications or specific drugs, so inform your doctor or pharmacist if you are taking other medications. Pregnant or breastfeeding women should not take this medication, and especially if planning pregnancy or currently pregnant, safe alternative treatments should be discussed with a doctor. Elderly patients should start this medication at a lower dose and gradually increase it, while carefully monitoring any electrolyte imbalances or changes in blood pressure. In case of an overdose, serious hypotension, dizziness, and renal dysfunction may occur, making it essential to visit a medical institution for appropriate treatment. This medication has not been proven safe and effective for use in children, and its use is not recommended. It is essential to keep this medication out of the reach of children and not to tamper with the container without proper guidance. Caution is advised when driving or operating machinery due to possible dizziness or drowsiness.

Serious side effects

Urticaria, severe swelling (angioedema), chest tightness, difficulty breathing, cold sweat, pallor, severe rash with fever, blistering, skin peeling, oral/ocular mucosal pain, difficulty breathing or shortness of breath, asthmatic attack, respiratory abnormalities accompanied by cough and fever, jaundice (yellowing of skin or eyes), generalized fatigue, sudden and severe headache, seizures, confusion, visual disturbances, paralysis, significantly reduced urine output

Mild side effects

Constipation, nausea, asthenia, nasopharyngitis, back pain, dizziness, headache, proteinuria, increased serum creatine phosphokinase (CPK), atrial fibrillation, retinal hemorrhage, drowsiness, fatigue, insomnia, paresthesia, erectile dysfunction, malaise, pain, arthralgia, muscle cramps, myalgia, hypoglycemia, appetite loss, vomiting, abdominal pain, vasculitis, dermatitis, rash, pruritus, angioedema, flushing, erythema, polymorphic erythema, visual disturbances, conjunctivitis,

This medication is sensitive to light and should be stored in a container that does not allow light in. It is also recommended to keep it at room temperature between 1 to 30 degrees Celsius. This will help maintain the efficacy of the medication for a longer period.

Appearance

White oval biconvex tablet

Package unit

30 tablets (10 tablets/PTP × 3) / carton