Sinjiroxine Tablets 75 Micrograms (Levothyroxine Sodium Hydrate)

Adult dose

Adults: The usual dose is 25-400㎍ of levothyroxine sodium orally once daily. The usual initial dose is 25-100㎍, and the maintenance dose is 100-400㎍. The dose may be adjusted appropriately according to age and symptoms.

This medication should not be used by individuals with normal thyroid function for the purpose of weight loss. Taking thyroid hormones along with sympathomimetic amines can lead to severe toxicity, which is very dangerous. Patients with heart disease or those with acute myocardial infarction, myocarditis, severe angina, or heart failure accompanied by tachycardia may experience worsening conditions if this medication is used and should not use it. Additionally, it should not be used by those with hyperthyroidism, adrenal insufficiency, thyroid toxicity, or individuals allergic to this medication. Patients with lactose intolerance or specific genetic metabolic disorders must not take this medication and should consult a doctor. Patients with hypertension, angina, cardiovascular disease, adrenal cortex insufficiency, diabetes, the elderly, and severe hypothyroidism should use this medication cautiously, and it is important to gradually increase the dosage and maintain the minimum effective dose. Overdosing on this medication can result in various side effects, including palpitations, arrhythmias, insomnia, headaches, vomiting, diarrhea, myalgia, and more, so immediate consultation with medical personnel is required if symptoms occur. Patients with hypothyroidism should start with a low dose and gradually increase while monitoring their condition, and diabetic patients should be attentive to blood sugar control. Cardiovascular disease patients should reduce the dosage if chest pain or worsening symptoms occur. This medication can interact with several drugs such as coumarin anticoagulants, sympathomimetic agents, cardiac glycosides, hypoglycemic agents, iron supplements, anticonvulsants, estrogens, and propranolol, so consultation with a doctor or pharmacist is required before concurrent use. It is advisable not to stop treatment during pregnancy, and nursing mothers should also use it with caution. In children, early initiation of treatment for hypothyroidism is essential, as overtreatment can affect growth. The elderly, having diminished bodily functions, should start with lower doses and gradually increase. This medication can affect thyroid function test results, so it's important to inform medical personnel if currently taking it before testing, and consideration should be given to avoiding testing or opting for alternative tests when taking medications containing biotin. In case of overdose, appropriate emergency measures such as inducing vomiting, gastric lavage, oxygen supply, and administering beta-blockers are necessary.

• Palpitations
• increased heart rate
• arrhythmia
• angina
• increased pulse pressure
• tremors
• insomnia
• headache
• dizziness
• sweating

This medication is sensitive to light, so it should be stored in a container that blocks light. It is best to maintain the storage temperature between 1 degree and 30 degrees Celsius at room temperature. Storing it this way helps maintain the medication's efficacy.

Appearance

Green oval tablets

Package unit

For domestic use: 100 tablets/bottle, 300 tablets/bottle, for export: 50 tablets (10 tablets/PTP×5), 100 tablets (10 tablets/PTP×10), 300 tablets/bottle