Solistop Tablet 10 Milligrams (Solifenacin Succinate)

Adult dose

The recommended dose for adults (including the elderly) is 5mg once daily. If necessary, the dose may be increased to a maximum of 10mg once daily. This medicine may be taken with or without food and should be swallowed whole with water. Dosage adjustment is required for the following patients. 1. Patients with renal impairment: No dose adjustment is necessary in patients with mild or moderate renal impairment (creatinine clearance>30ml/min). In patients with severe renal impairment (creatinine clearance≤30ml/min), administer with caution and do not exceed 5mg once daily. 2. Patients with hepatic impairment: No dose adjustment is necessary in patients with mild hepatic impairment. In patients with moderate hepatic impairment (Child-Pugh class B), administer with caution and do not exceed 5mg once daily. 3. Patients receiving a strong cytochrome P450 3A4 (CYP3A4) inhibitor : In patients receiving ketoconazole or another strong CYP3A4 inhibitor (e.g., ritonavir, nelfinavir, itraconazole), limit the maximum daily dose to 5mg.

This medication is used for regulating bladder function and should not be administered to patients with certain diseases or conditions. For example, patients with urinary retention symptoms, severe gastrointestinal disorders, myasthenia gravis, and glaucoma with high intraocular pressure should not use this medication. Additionally, patients undergoing hemodialysis or those with severely impaired liver and kidney function, as well as patients with certain genetic metabolic disorders, should also avoid this medication. There may be patients for whom this medication requires careful usage. For example, patients at risk of bladder outlet obstruction or reduced gastrointestinal motility, those with severe kidney or liver dysfunction, and patients taking specific strong medications should take this medication under close medical supervision. Side effects such as dry mouth, constipation, and blurred vision may occur due to this medication, and these side effects are more frequent with higher doses. Rarely, angioedema, allergic reactions, and serious gastrointestinal problems have been reported; thus, if unusual symptoms occur, medical consultation should be sought immediately. Care must be taken when driving or operating machinery, as drowsiness or blurred vision may occur. Taking other anticholinergic medications may enhance the effects or worsen side effects; therefore, it is essential to consult a doctor or pharmacist before taking any medications. In particular, if taken with certain medications that inhibit the enzymes that metabolize this medication in the liver, the blood concentration of this medication may increase, raising the risk of side effects and necessitating dosage adjustments. Pregnant women must be cautious as the safety of this drug has not been established, and nursing mothers should avoid its use, as it can be transmitted through breast milk and affect the baby. This medication should not be administered to children as its safety and efficacy have not been confirmed. In case of overdose, symptoms such as headache, dizziness, drowsiness, and blurred vision may appear, and it is crucial to visit a medical institution for appropriate treatment. Emergency treatments such as activated charcoal or other interventions may be necessary in case of overdose, and professional treatment may be required for severe symptoms.

• Dry mouth
• constipation
• blurred vision
• urinary retention
• dry eyes
• fecal impaction
• colonic obstruction
• bowel obstruction
• angioedema
• nausea

This medication should be stored in a tightly closed container to protect it from air and moisture, and it is safely stored at room temperature between 1 and 30 degrees Celsius.

Appearance

Bright pink round film-coated tablet

Package unit

100 tablets (10 tablets/PTP × 10)