AmoZaltan Plus Tablet 5/50/12.5 mg (Amlodipine, Losartan, Chlorthalidone)

Adult dose

This medication should be taken once daily, one tablet, with water, regardless of meals. It is recommended to take it at the same time each day (e.g., in the morning). For patients whose blood pressure is not controlled by the combination therapy of amlodipine/losartan, this drug at 5/50/12.5 mg should be administered, and adjustments to the dosage should be made considering the patient's blood pressure response, at intervals of at least two weeks. The maximum recommended dose of this medication is 5/100/25 mg.

This medication can cause serious harm to the fetus if taken during pregnancy, especially in the second and third trimesters, so usage should be stopped immediately upon confirmation of pregnancy. Patients with liver dysfunction or those with ongoing liver disease must be cautious as severe side effects such as hepatic coma may occur when taking this medication. Patients with severe kidney disease should use this medication cautiously, as some components may accumulate in the body and worsen kidney function. Patients who have hypersensitivity to any of the ingredients in this drug or specific allergies should not take it. Patients with severe hypotension or severe liver failure and kidney failure may also be at risk if using this drug, so it should not be administered. Patients with a history of specific heart valve diseases or vascular edema should avoid taking this medication. This medicine contains lactose, so it is safer for patients with lactose intolerance to avoid its use. Diabetic patients or those with moderate to severe kidney dysfunction should be cautious when taking this medication in combination with specific other medicines. Elderly patients or those at risk of electrolyte imbalances should periodically check their blood pressure and electrolyte status while taking this medication. This drug has a strong blood-pressure-lowering effect, so side effects such as dizziness, headache, and hypotension may occur; caution is required during driving or operating machinery. Adverse reactions while taking this drug can include dyspepsia, constipation, muscle pain, dizziness, headache, and skin rash; if symptoms are severe, consultation with a doctor is recommended. Taking potassium supplements or potassium-rich foods indiscriminately during the use of this medication can raise potassium levels in the blood to dangerous levels and should be discussed with a doctor. In case of overdose, severe hypotension, tachycardia, and coma may occur, so it is important to adhere to the prescribed dosage and contact a healthcare institution immediately if an overdose occurs. The safety and efficacy of this medication in children and adolescents under 18 years have not been established, and its use is not recommended. For breastfeeding women, it is advisable to stop breastfeeding when using this medication, as it may be excreted in breast milk. This medication should be stored in a cool place, away from direct sunlight and moisture, and out of the reach of children. It is crucial to consult a physician or pharmacist before use to verify interactions with other medications and individual health conditions.

Serious side effects

Urticaria, severe swelling (edema), chest tightness, difficulty breathing, cold sweat, pallor, severe allergic reaction, severe rash accompanied by high fever, blistering, skin peeling, pain in mouth/eyes mucosa, severe skin adverse reactions, shortness of breath or difficulty breathing, asthma attack, respiratory abnormalities accompanied by cough and fever, breathing problems, jaundice (yellowing of the skin or eyes), profound lethargy, liver abnormalities (jaundice), sudden and

Mild side effects

• Dizziness
• headache
• weakness
• chest pain
• nasopharyngitis
• vaginal infection
• muscle strain
• elevated ALT
• elevated AST
• increased cholesterol

This medication must be stored in a tightly closed container to prevent contact with air or moisture. Storing it at room temperature, between 1 to 30 degrees Celsius, is recommended.

Appearance

White oval film-coated tablet

Package unit

30 tablets/bottle