Amazaltan Plus Tablet 5/100/25 mg (Amlodipine, Losartan, Chlorothalidone)

Adult dose

This medication should be taken once daily as one tablet, with or without food, preferably at the same time each day (e.g., in the morning). For patients whose blood pressure is not controlled with amlodipine/losartan combination therapy, a dose of this medication of 5/50/12.5 mg is given, and the dosage should be adjusted considering the patient's blood pressure response at intervals of more than 2 weeks. The maximum recommended dose of this medication is 5/100/25 mg.

This medication can pose serious risks to fetuses and newborns during pregnancy, so it should be discontinued immediately if pregnancy is confirmed. Patients with impaired liver function or progressive liver disease may experience serious side effects, such as hepatic coma, while using this medication. Patients with severe kidney disease should use this medication cautiously as the diuretic component may increase blood urea nitrogen levels, potentially burdening kidney function. Patients who are hypersensitive to any component of this medication, those with certain genetic lactose intolerance, pregnant women or women who might become pregnant, and nursing mothers should not use this product. Patients with severe hypotension, severe liver or kidney failure, specific heart diseases, or a history of angioedema should not take this medication. Elderly patients, those with hyperkalemia, kidney failure, liver impairment, heart valve stenosis, etc., should have their blood pressure and electrolyte status monitored closely when receiving this medication. As this medication lowers blood pressure, symptoms such as dizziness, headache, and hypotension may occur, along with potential side effects like indigestion, constipation, and fatigue. During the course of treatment, potassium supplements or salt substitutes containing potassium should not be taken without consulting a physician. Use of this medication is advised against during pregnancy or breastfeeding; if it is absolutely necessary, consultation with a physician is required. Safety and effectiveness of this medication have not been established in pediatric patients under 18 years of age, so it is not recommended. In elderly patients, it is important to start with a low dose and administer cautiously to prevent hypotension or electrolyte imbalances. In case of overdose, severe hypotension, altered consciousness, and arrhythmias may occur, so immediate medical attention is necessary. This medication should be stored away from direct sunlight in a cool, dry place, and out of reach of children.

Serious side effects

Hives, severe swelling (edema), tightness in the chest, difficulty breathing, cold sweat, pallor, severe rash accompanied by high fever, blisters, skin peeling, mucosal pain in the mouth/eyes, shortness of breath or difficulty breathing, asthma attacks, respiratory anomalies with cough and fever, yellowing of the skin or eyes (jaundice), extreme general weakness, sudden and very severe headache, thunderclap headache, seizures, altered consciousness, vision abnormalities, paralysis, numbness

Mild side effects

• Dizziness
• headache
• weakness
• constipation
• indigestion
• upper abdominal discomfort
• esophagitis
• chest pain
• influenza
• nasopharyngitis

This medication can be sensitive to air and moisture, so it should be stored in a tightly sealed container. The storage temperature should be maintained between 1 and 30 degrees Celsius at room temperature. Storing it this way helps preserve the medication's effectiveness over time.

Appearance

Yellow oval film-coated tablet

Package unit

30 tablets/bottle