Loxorifen Tablet (Sodium Loxoprofen Hydrate)

Adult dose

1. For indications 1 and 2: 1) Adults: Administer 60 mg of Sodium Loxoprofen (anhydrous) orally three times a day. For a single treatment, administer 60-120 mg orally. 2. For indication 3: 1) Adults: Administer 60 mg of Sodium Loxoprofen (anhydrous) orally. In principle, it can be administered twice a day, with a maximum of 180 mg daily. On an empty stomach, it is generally advisable to avoid the medication.

Patients who drink more than three cups of alcohol regularly every day should consult with a doctor or pharmacist before taking this medication or other antipyretic analgesics. Those who frequently consume alcohol may have an increased risk of gastrointestinal bleeding when taking this medication. This medication can affect the cardiovascular system and may increase the risk of cardiovascular diseases such as myocardial infarction or stroke. Patients with cardiovascular conditions or risk factors should be particularly cautious, and both the doctor and the patient should carefully monitor for any cardiovascular symptoms during treatment. This medication can also affect the gastrointestinal tract, potentially leading to serious issues such as bleeding, ulcers, or perforation in the stomach or intestines. These adverse reactions may occur even in the absence of symptoms, so signs of gastrointestinal bleeding should be closely monitored during administration. Elderly patients or those with a history of gastrointestinal disorders should be particularly cautious. Patients with peptic ulcers, severe blood disorders, severe liver dysfunction, kidney dysfunction, heart failure, or those allergic to this medication or its components should not take this medication. Additionally, patients with allergic reactions to aspirin or other non-steroidal anti-inflammatory drugs should avoid using it. When administering this medication, patients with a history of peptic ulcers or abnormalities in the liver, kidneys, and blood, patients with hypertension, elderly patients, and women in the early or mid stages of pregnancy should be used cautiously, and regular checks should be done according to the doctor's instructions if necessary. During administration, symptoms of hypersensitivity such as rash, itching, hives, difficulty breathing, and low blood pressure may occur, so if these symptoms arise, the medication should be stopped immediately and medical consultation sought. This medication may cause gastrointestinal symptoms such as abdominal pain, nausea, vomiting, and diarrhea, and in severe cases, gastrointestinal bleeding or perforation may occur, so caution is needed. Neurological symptoms such as drowsiness, dizziness, and headaches may also appear, so caution is necessary when driving or operating machinery. There may be abnormalities in liver or kidney function, so if any unusual symptoms occur, medical personnel should be informed immediately, particularly watching for symptoms of liver dysfunction such as jaundice or fatigue and deterioration of kidney function. The risk of adverse effects increases when this medication is taken with other non-steroidal anti-inflammatory drugs, so it is advisable not to combine them. This medication may interact with antihypertensive drugs, diuretics, anticoagulants, antibiotics, etc., so if you are taking these medications, you must inform your doctor. It should not be used in the late stages of pregnancy as it may be dangerous for the fetus, and women who are pregnant or breastfeeding should consult with their doctor before taking this medication. Safety for children has not been established, so it should be administered cautiously to children. Elderly patients are at a higher risk for adverse effects when taking this medication, so particular caution is necessary. Lastly, this medication should be stored out of reach of children and should not be transferred to another container for safety.

Serious side effects

Hives, severe swelling, chest tightness, difficulty breathing, cold sweat, pallor, severe rash with high fever, blisters, skin peeling, pain in oral/ocular mucosa, shortness of breath or difficulty breathing, asthma attacks, respiratory issues with coughing and fever, yellowing of the skin or eyes (jaundice), extreme lethargy, sudden and severe headaches, thunderclap headache, seizures, disorientation, visual disturbances, paralysis, reduced urine output.

Mild side effects

• Sometimes rash
• itching
• fever
• abdominal pain
• unpleasant sensation in the stomach
• loss of appetite
• nausea
• vomiting
• diarrhea
• constipation

This medication should be stored in a tightly closed container to avoid exposure to air or moisture. It is best to maintain the storage temperature between 1 to 30 degrees Celsius.

Appearance

White round tablet

Package unit

30 tablets/bottle, 500 tablets/bottle