Twinbeta Tablets 40/5 mg

Adult dose

The recommended dosage of this medication is 1 tablet once daily, to be taken with water regardless of meals. It is recommended to take it at the same time every day (e.g., in the morning). Patients with renal impairment do not require dose adjustment for mild to moderate renal impairment; however, in cases of severe impairment, it is recommended to start with a lower dose and gradually increase. For patients with liver impairment, the daily dosage should not exceed 40 mg. Elderly patients are generally advised to follow the usual dosing regimen for amlodipine, but caution is advised during dose escalation.

Child dose

The safety and efficacy in pediatric patients under 18 years of age have not been established, therefore administration is not recommended.

This medication should not be used during pregnancy, especially in the second and third trimesters, as it can cause serious harm to the fetus; therefore, it should not be taken by women who are pregnant or may become pregnant. It should not be administered to patients who are allergic to any components of this medication, those with specific heart diseases, severely impaired liver or kidney function, and nursing mothers. Patients with impaired liver function, gastrointestinal diseases, renal vascular hypertension, etc., should exercise special caution when using this medication, and the elderly should be treated carefully. While taking this medication, side effects such as dizziness or peripheral edema may occur, and if these symptoms are severe, consultation with a doctor is necessary. Blood pressure may drop too low; therefore, patients who are particularly depleted of fluids or salts should verify their condition before taking this medication. There is a risk of elevated potassium levels; hence, blood tests are required when taken with potassium supplements or specific diuretics to monitor potassium levels. Patients with diminished kidney function should also periodically check for changes in kidney function while taking this medication. Interaction with other antihypertensive drugs or specific medications may occur, so it is essential to inform the doctor or pharmacist of any other medications being taken. Drowsiness or dizziness may occur when taking this medication; therefore, caution should be exercised when driving or operating dangerous machinery. In cases of overdose, severe hypotension, dizziness, or heart abnormalities may occur, so it is crucial to adhere strictly to the dosage, and if any abnormal symptoms appear, immediate consultation with medical personnel is required. It is not recommended for children as safety and efficacy have not been established. This medication should be stored out of reach of children, and transferring to another container should be avoided.

Serious side effects

Hives, severe swelling (angioedema), chest tightness, difficulty breathing, sweating, pallor, severe rash accompanied by fever, blisters, skin peeling, mucosal pain in the mouth/eyes, difficulty breathing or shortness of breath, asthma attack, respiratory abnormalities accompanied by cough and fever, yellowing of skin or eyes (jaundice), severe malaise, sudden and severe headache, thunderclap headache, seizures, confusion, vision problems, paralysis,

Mild side effects

• Dizziness
• peripheral edema
• fainting
• drowsiness
• headache
• sensory disturbances
• taste disturbances
• tremors
• visual disturbances
• vertigo

This medication may be sensitive to light; thus, it should be stored in a light-blocking container. Moreover, it is advisable to store it at room temperature between 1 and 30 degrees Celsius. Proper storage will help maintain the medication's effectiveness.

Appearance

White and light blue, oval-shaped, double convex tablet

Package unit

30 tablets/bottle, 100 tablets/bottle