Tugenonjeong 10/8 mg

Adult dose

Tugenonjeong 10/8 mg is administered only to adults, and the dosage should be individualized based on the efficacy and tolerability of each component, Candesartan cilexetil and Rosuvastatin. ○ Candesartan cilexetil 1. Essential Hypertension - Adults: An initial dose and maintenance dose of 8 to 16 mg daily is recommended. If blood pressure is not adequately controlled after 4 weeks at a dose of 16 mg, the maximum dose may be increased to 32 mg once daily. 2. The initial dose does not need to be adjusted for the elderly. 3. For patients with intravascular volume depletion, administer an initial dose of 4 mg with caution due to the risk of hypotension. 4. For patients with kidney dysfunction, including those on dialysis, the initial dose is 4 mg, and the dose should be adjusted based on the patient's response. Experience in patients with severe or end-stage renal disease (creatinine clearance < 15 mL/min) is limited. 5. For patients with liver dysfunction, the initial dose for patients with mild to moderate liver dysfunction is 2 mg once daily, and the dose should be adjusted based on the patient's response. No experience is available for use in patients with severe liver dysfunction. 6. Children: The safety and efficacy in individuals younger than 18 years have not been established.

Child dose

The safety and efficacy in pediatric patients (individuals younger than 18 years) have not been established.

This medication can cause serious harm to the fetus and newborn when used during pregnancy, especially during the second and third trimesters, so it should be discontinued immediately upon confirmation of pregnancy. Women of childbearing potential should use appropriate contraceptive methods, and pregnant or breastfeeding women are advised not to take this medication. Patients with allergies to this medication or its components, severely impaired liver or kidney function, or a history of myopathy or hereditary angioedema should not take it. Caution is required for elderly patients, patients with hyperkalemia, and those with mildly impaired liver or kidney function, as well as patients with heart disease, and regular monitoring is recommended. This medication can cause side effects such as muscle pain or weakness, headache, dyspepsia, and itching, so patients should consult a doctor immediately if symptoms occur. Particularly, if muscle-related symptoms are severe or muscle enzyme levels are significantly increased, they should stop taking the medication and seek medical attention. Interactions may occur when taking this medication with other drugs, so patients should inform healthcare professionals of any other medications they are taking. This medication may cause dizziness or lethargy while driving or operating machinery, so caution is necessary. Keep out of reach of children and store in the original container for safety.

Serious side effects

Urticaria, angioedema, chest discomfort, difficulty breathing, angioedema (swelling of face, lips, tongue, pharynx, and larynx), severe allergic reactions, severe rash with fever, blisters, skin peeling, pain of oral/ocular mucosa, severe skin reactions, jaundice, yellowing of the skin or eyes, liver abnormalities, sudden and severe headache, thunderclap headache, seizures, altered consciousness, visual disturbances, paralysis, severe neurological symptoms

Mild side effects

• Headache
• dizziness
• rhinitis
• hives
• local infections
• periodontitis
• fatigue
• inflammation
• foreign body sensation
• itching

This medication may be sensitive to air and moisture, so it should be kept in a tightly sealed container. It is also advisable to store it at room temperature between 1 and 30 degrees Celsius, avoiding excessively hot or cold places.

Appearance

Pink round film-coated tablets

Package unit

30 tablets (10 tablets/PTP x 3)