Lokan Duo Tablets 10/16 mg

Adult dose

The recommended initial and maintenance dose of Candesartan Cilexetil is 8-16 mg orally once daily. If blood pressure control is difficult, the dose may be increased to a maximum of 32 mg once daily. For heart failure, the initial dose is 4 mg once daily, and the dose may be doubled at intervals of more than 2 weeks, with a maximum of 32 mg once daily. Rosuvastatin should be started at 5 mg once daily at any time of day.

Child dose

Safety and efficacy for adolescents and children under 18 years of age have not been established.

This medication can cause serious harm to the fetus and newborn during pregnancy, so it should be discontinued immediately if pregnancy is confirmed. Individuals with allergic reactions to this medication or with liver disease, severe liver impairment, myopathy, or severe renal impairment should not take it. Women of childbearing age should use appropriate contraceptive methods considering the possibility of pregnancy, and if planning pregnancy, should consult a doctor. Elderly patients, those with reduced liver function, or patients with hyperkalemia should use this medicine with caution, and it is important to regularly monitor liver and kidney function through blood tests. If symptoms such as muscle pain, muscle weakness, or muscle cramps occur, immediate medical attention is required, and in severe cases, the medication may need to be discontinued. This medication may increase liver enzyme levels, thus regular liver function tests are necessary, and if symptoms of liver damage appear, immediate consultation with a doctor is required. As it can lower blood pressure, caution should be exercised in cases of hypotension, dizziness, or fainting, and care should be taken while driving or operating machinery. When taken with other antihypertensives, diuretics, or potassium-sparing agents, potassium levels in the blood may increase, necessitating regular monitoring. During treatment, avoid vigorous exercise or activities that stress the muscles, and consult medical professionals immediately if muscle-related symptoms worsen. Patients with lactose intolerance should not take this medication, and due to potential drug interactions, it's essential to inform a doctor or pharmacist if taking other medications. Pregnant and breastfeeding women should not take this medication, and if breastfeeding, discussions regarding alternative medications should be held.

Serious side effects

Hives, angioedema (swelling of the face, lips, tongue, throat), shock, fainting, loss of consciousness, severe rash with high fever, blisters, skin peeling, pain in oral/ocular mucosa, rash, thrombocytopenia, Stevens-Johnson syndrome, eosinophilia with systemic symptoms Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS), jaundice, hepatitis, severe skin adverse reactions, abnormal liver function tests, liver failure, interstitial pneumonia, dyspnea, shortness of breath

Mild side effects

• Headache
• dizziness
• orthostatic dizziness
• nasopharyngitis
• hordeolum
• local infections
• periodontitis
• fatigue
• inflammation
• foreign body sensation

This medicine should be stored in a tightly closed container to protect it from air and moisture. It is important to maintain a storage temperature between 1 degree and 30 degrees Celsius at room temperature. This way, the effectiveness of the medication can be preserved for a longer period.

Appearance

Yellow round film-coated tablet

Package unit

30 tablets (10 tablets/PTP X 3)