Lokan Duo Tablet 20/32 Milligrams

Adult dose

For the treatment of essential hypertension with Candesartan Cilexetil, an initial and maintenance dosage of 8 to 16 mg orally once daily is recommended. If blood pressure is not controlled after 4 weeks of treatment at 16 mg once daily, the dose may be increased to a maximum of 32 mg once daily. For heart failure treatment, the initial dose is 4 mg once daily, and the dose may be doubled at intervals of at least 2 weeks, up to a maximum of 32 mg once daily.

Child dose

Safety and efficacy in children and adolescents under 18 years of age have not been established.

This medication can cause serious harm to the fetus, particularly when taken during the second and third trimesters of pregnancy. Therefore, it should be discontinued immediately if pregnancy is confirmed. This medication should not be used in patients with specific diseases, such as those with severe liver dysfunction, significantly impaired kidney function, or certain muscle diseases. This medication should be used with caution in the elderly or in patients with high potassium levels, and those with mild liver dysfunction, requiring regular blood tests and monitoring of physical condition. Muscle-related side effects may occur, so if symptoms like muscle pain or weakness appear, a doctor should be consulted immediately, and in severe cases, the medication should be discontinued. This medication can also affect liver function; therefore, it is important to conduct regular liver function tests both before and during treatment. There may be interactions with other medications, so be sure to inform medical staff of any other medications being taken, especially when used in combination with certain antibiotics, antifungals, immunosuppressants, and fibrate class drugs. Women of childbearing potential should use appropriate contraception while taking this medication, and nursing mothers are advised to avoid taking this drug. Safety and efficacy have not been established in children and therefore should not be recommended. In cases of overdose, appropriate treatment is required according to symptoms, and since this drug is not removed by hemodialysis, professional medical management is necessary. Dizziness or fatigue may occur while taking this medication, so caution should be exercised when driving or operating machinery. Keep this medicine out of the reach of children and store it in its original container to prevent misuse.

Serious side effects

Urticaria, angioedema, chest tightness, difficulty breathing, cold sweat, pallor, severe allergic reactions, severe rash with high fever, blistering, exfoliative skin reactions, mucosal pain in mouth/eyes, severe cutaneous adverse reactions, shortness of breath or difficulty breathing, asthma attacks, respiratory abnormalities with cough + fever, breathing problems, yellowing of the skin or eyes (jaundice), extreme fatigue, liver abnormalities (jaundice), sudden and severe symptoms

Mild side effects

• Headache
• dizziness
• rhinitis
• miliary cysts
• local infections
• periodontitis
• chest discomfort
• fatigue
• inflammation
• foreign body sensation

This medication may be sensitive to air or moisture, so it should be stored in a tightly sealed container. It is best to maintain a storage temperature between 1 and 30 degrees Celsius to preserve the effectiveness and safety of the medication for an extended period.

Appearance

Pink round film-coated tablet

Package unit

30 tablets (10 tablets/PTP X 3)