Viewing nowCombinationLokan Duo Tablets 5/8 mg
Rosuvastatin Calcium 5.2mg · Candesartan Cilexetil 8mg
Tablet · Prescription medication · Combination
AlboGen Korea Co., Ltd.

MFDS item code 201702397 · Approved 2017.05.16 · Insurance code 652606340
Treatment of hypertension and heart failure (including reduction of cardiovascular disease risk)
This medication is suitable for patients who require the combined use of two drugs, Candesartan Cilexetil and Rosuvastatin. Candesartan Cilexetil is mainly used for patients with essential hypertension and heart failure with decreased left ventricular systolic function (especially when additional treatment is needed or when tolerance to ACE inhibitors is reduced). Rosuvastatin is prescribed for patients with hypercholesterolemia and dyslipidemia when dietary therapy and exercise are difficult to control or need supplementation. Additionally, it helps in the treatment of homozygous familial hypercholesterolemia or to slow the progression of atherosclerosis. For adult patients at risk of cardiovascular disease, it is used to reduce the risk of stroke, myocardial infarction, and revascularization. By administering these two drugs together, blood pressure and blood lipid levels can be effectively controlled, improving cardiovascular health.
Candesartan Cilexetil: For adults with essential hypertension, the recommended dosage is 8-16 mg orally once daily. If blood pressure is not controlled, the dose can be increased up to 32 mg once daily. The initial dose for adults with heart failure is 4 mg once daily, and the dose can be doubled at intervals of at least 2 weeks. Rosuvastatin: An initial dose of 5 mg should be administered once daily at any time of the day, and if necessary, it can be increased to 1.
Safety and efficacy in adolescents and children under 18 years have not been established.
This medication may cause serious harm to the fetus and newborn if taken during pregnancy, so it should be discontinued immediately upon confirmation of pregnancy. Use is contraindicated in individuals with hypersensitivity to this medication, liver disease, severe liver dysfunction, kidney failure, pregnant or breastfeeding women, and certain genetically predisposed lactose intolerant patients. Elderly patients, those with hyperkalemia, and patients with mild to moderate liver dysfunction should use this medication cautiously, especially if experiencing symptoms of myalgia or myopathy, in which case immediate consultation with healthcare professionals is necessary. This medication may cause muscle-related side effects, so muscle enzyme levels should be tested before and during use, and any symptoms of myalgia or weakness should be reported to a physician immediately. Liver function abnormalities may occur, so periodic checking of liver enzyme levels is necessary, and the medication should be discontinued if liver function deteriorates significantly. This medication may interact with other drugs, so patients should inform healthcare professionals about any other medications they are taking, particularly if using potassium-sparing diuretics, lithium, or nonsteroidal anti-inflammatory drugs. Women who may become pregnant should use appropriate contraception, and nursing mothers are advised to avoid using this medication. Safety and efficacy have not been established for children, and it is not recommended for use. In case of overdose, symptoms such as low blood pressure and dizziness may occur, necessitating immediate medical attention. Dizziness or fatigue may occur while taking this medication, so patients should be cautious when driving or operating machinery. This medication should be kept out of the reach of children, and it is not recommended to transfer the medicine to another container.
Hives, severe swelling (edema), chest tightness, difficulty breathing, cold sweat, pallor, severe rash with fever, blisters, peeling skin, pain in mucous membranes of the mouth/eyes, shortness of breath or difficulty breathing, asthma attack, respiratory abnormalities with cough and fever, jaundice (yellowing of skin or eyes), extreme lethargy, sudden and severe headache, thunderclap headache, seizures, confusion, visual disturbances, paralysis, urination.
Not everyone experiences these, and they can vary from person to person.
This medication should be stored in a tightly sealed container to prevent exposure to air and light. Additionally, it is important to store it at a temperature between 1 and 30 degrees Celsius to maintain its effectiveness.
Pink round film-coated tablet
30 tablets (10 tablets/PTP X 3)
Even with the same ingredient, strength, dosage form and how it is taken can differ.
Viewing nowCombinationRosuvastatin Calcium 5.2mg · Candesartan Cilexetil 8mg
Tablet · Prescription medication · Combination
AlboGen Korea Co., Ltd.
CombinationRosuvastatin Calcium 20.8mg · Candesartan Cilexetil 32mg
Tablet · Prescription medication · Combination
Albogen Korea Co., Ltd.
CombinationRosuvastatin Calcium 10.4mg · Candesartan Cilexetil 16mg
Tablet · Prescription medication · Combination
Alvogen Korea Co., Ltd.
CombinationRosuvastatin Calcium 10.4mg · Candesartan Cilexetil 8mg
Tablet · Prescription medication · Combination
Alvogen Korea Co., Ltd.
CombinationRosuvastatin Calcium 10.4mg · Candesartan Cilexetil 16mg
Tablet · Prescription medication · Combination
Hanin Pharmaceutical Co., Ltd.
CombinationRosuvastatin Calcium 10.4mg · Candesartan Cilexetil 8mg
Tablet · Prescription medication · Combination
Hanin Pharmaceutical Co., Ltd.
CombinationRosuvastatin Calcium 5.2mg · Candesartan Cilexetil 8mg
Tablet · Prescription medication · Combination
Hanin Pharmaceutical Co., Ltd.
CombinationRosuvastatin Calcium 20.8mg · Candesartan Cilexetil 32mg
Tablet · Prescription medication · Combination
Hwanin Pharmaceutical Co., Ltd.
Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.
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For anything that needs medical judgment, consult a doctor or pharmacist.
This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.