Soul-Q 5 mg tablets (Solifenacin Succinate)

Adult dose

For adults (including the elderly), the recommended dose is 5mg once daily. If necessary, the dose may be increased to a maximum of 10mg once daily. This medicine may be taken with or without food and should be swallowed whole with water. 1. Patients with renal impairment No dose adjustment is necessary in patients with mild or moderate renal impairment (creatinine clearance>30ml/min). Use with caution in patients with severe renal impairment (creatinine clearance≤30ml/min), and do not exceed 5mg once daily. 2. Patients with hepatic impairment No dose adjustment is necessary in patients with mild hepatic impairment. Use with caution in patients with moderate hepatic impairment (Child-Pugh Class B), and do not exceed 5mg once daily. 3. Patients taking potent cytochrome P450 3A4 (CYP3A4) inhibitors For patients taking ketoconazole or another potent CYP3A4 inhibitor (e.g., ritonavir, nelfinavir, itraconazole), limit the maximum daily dose to 5mg.

This medication should not be used in patients with certain diseases or conditions. For example, patients with urinary retention or severe gastrointestinal issues, myasthenia gravis, closed-angle glaucoma, those having hypersensitivity to this medication, patients undergoing dialysis, and those with severe liver or kidney disorders may be at risk if they take this medication. Moreover, caution should be exercised in patients with a narrow bladder outlet leading to urinary retention, those with gastrointestinal obstruction or risk of reduced gastrointestinal motility, severe kidney impairment, moderate liver impairment, and patients taking certain strong medications. Common side effects of this medication may include dry mouth, constipation, blurred vision, urinary retention, dry eyes, etc. The incidence of side effects may increase with high dosages, so be careful. Rarely, serious allergic reactions such as angioedema and anaphylaxis have been reported, necessitating immediate discontinuation of the drug and consultation with healthcare professionals. Special attention is needed in patients with cardiac arrhythmias or specific electrolyte imbalances as heart rhythm disorders may occur. Additionally, there is a risk of accidents due to drowsiness or blurry vision when driving or operating machinery, so caution is advised. Potential interactions with other anticholinergic drugs may increase the effectiveness or worsen side effects, while the effect of drugs promoting gastrointestinal motility may be reduced. This medication is metabolized by certain enzymes in the liver (CYP3A4), so taking it with drugs that strongly inhibit this enzyme may increase drug concentration and the risk of side effects. Women who are pregnant or breastfeeding should use this medication with caution, particularly during breastfeeding, as it may be passed into breast milk and affect the infant. The safety and efficacy in children have not been established, and this medication should not be administered to children. In case of overdose, symptoms may include headache, dizziness, drowsiness, and blurred vision, and in severe cases, professional treatment may be required. In the event of an overdose, immediate consultation with a healthcare institution for appropriate treatment is necessary.

• Dry mouth
• constipation
• blurred vision
• urinary retention
• dry eyes
• fecal impaction
• colonic obstruction
• intestinal obstruction
• vascular neurogenic edema
• nausea

This medication may be sensitive to air or moisture, thus it should be stored in a tightly closed container. Additionally, avoid places that are too hot or too cold, and it is advisable to store it at room temperature between 1 to 30 degrees Celsius.

Appearance

Bright yellow round film-coated tablets

Package unit

100 tablets/box [10 tablets/PTP X 10]