Medication info

Zinc Edition Co., Ltd. (Zinc Sulfate Hydrate)

Prescription medicationInjections
Ingredient · strength
Zinc Sulfate Hydrate›4.4mg / 1mL
Manufacturer / importer
(주)인트로바이오파마
Appearance
A colorless, odorless, transparent liquid contained in a colorless, transparent vial injection.
Packaging
Vial package - 10 milliliters/vial [10mL × 10 vials], Vial package - 15 milliliters/vial [15mL × 10 vials]
Approval status
Active

MFDS item code 201702157 · Notified 2017.04.27

Summary

Main use
Prevention of zinc deficiency and improvement of nutritional status
Who uses it
Adults · Children
Adult dosage
Use as prescribed by a physician, adjusting the dosage based on plasma trace element levels. Metabolically stable TPN patients: 2.5 to 4 mg/day Adult patients with intestinal fluid loss: an additional 12.2 mg/L (fluid loss amount) or an additional 17.1 mg/kg (excretion amount) Acute burn condition: 4.5 to 6 mg/day
Children's dosage
Children under 5 years: 100 ug/kg/day Premature infants weighing less than 3 kg: 300 ug/kg/day

Ingredients

Manufacturer
(주)인트로바이오파마

Efficacy & effects

Prevention of zinc deficiency and improvement of nutritional status

View approved original text

It is important to supplement zinc for patients receiving Total Parenteral Nutrition (TPN). Zinc is an essential mineral for wound healing and maintaining immune function. Zinc deficiency may occur with prolonged TPN, making proper zinc supplementation necessary to prevent it. Zinc supplementation helps improve patients' overall recovery and health.

Dosage and Administration

Adult dosage

Use as prescribed by a physician, adjusting the dosage based on plasma trace element levels. Metabolically stable TPN patients: 2.5 to 4 mg/day Adult patients with intestinal fluid loss: an additional 12.2 mg/L (fluid loss amount) or an additional 17.1 mg/kg (excretion amount) Acute burn condition: 4.5 to 6 mg/day

Children's dosage

Children under 5 years: 100 ug/kg/day Premature infants weighing less than 3 kg: 300 ug/kg/day

Precautions

This medication should not be injected directly into peripheral veins in an undiluted state. The reason is that doing so may cause phlebitis or potentially harm the kidneys due to zinc. The amount of zinc included in this medication is very small, so toxic symptoms are rarely seen. It is important to maintain a sterile environment when mixing this medication, and it is recommended to work in a laminar flow hood if possible. Before injection, the medication must be visually inspected for any precipitate or discoloration. When administering zinc, copper levels may decrease, so it is necessary to check copper and zinc blood levels at regular intervals. This medication is excreted via the intestines and kidneys, so caution is necessary for patients with problems in these excretory organs to prevent zinc accumulation in the body. Women who are pregnant or may become pregnant should only use this medication if the therapeutic benefits outweigh the risks. Zinc can cross the placenta and is present in breast milk, so pregnant and nursing women should exercise caution. In cases of overdose, symptoms such as nausea, vomiting, dehydration, electrolyte imbalance, dizziness, abdominal pain, drowsiness, and ataxia may occur, and in severe cases, can be fatal. Calcium intake may help reduce zinc toxicity. This medication should be stored out of reach of children and kept in a dry place at room temperature. Furthermore, since this medication does not contain preservatives, any unused portion must be discarded.

Side effects and when to seek care immediately

Mild side effects

  • Nausea
  • vomiting
  • dehydration
  • electrolyte imbalance
  • dizziness
  • abdominal pain
  • drowsiness
  • ataxia

Not everyone experiences these, and they can vary from person to person.

Storage

This medication should be stored in a sealed container to prevent air and moisture ingress, and it is appropriate to keep it at a temperature between 1 degree and 30 degrees Celsius at room temperature. Storing it this way can help maintain the drug's effectiveness for a long time.

Appearance and packaging

Appearance

A colorless, odorless, transparent liquid contained in a colorless, transparent vial injection.

Package unit

Vial package - 10 milliliters/vial [10mL × 10 vials], Vial package - 15 milliliters/vial [15mL × 10 vials]

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

Questions about this medicine

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For anything that needs medical judgment, consult a doctor or pharmacist.

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.