Medication info
Twinheart Tablets 40/10 mg

Twinheart Tablets 40/10 mg

Prescription medication경구
Ingredient · strength
Telmisartan›40mg / 1 tabletAmlodipine Besylate›13.87mg / 1 tablet
Manufacturer / importer
(주)동구바이오제약
Appearance
Biconvex oval double tablet with one side white and the other side pale blue
Packaging
30 tablets/box [10 tablets/Alu-Alu X 3]
Approval status
Active

MFDS item code 201702117 · Approved 2017.04.26 · Insurance code 657307050

Summary

Main use
Improvement in blood pressure control for essential hypertension
Who takes it
Adults · Children
Adult dose
The recommended dose is 1 tablet once daily, taken with water regardless of meals. It is advised to take it at the same time daily (e.g., morning). In patients with severe renal impairment, treatment should begin at a lower dose and be gradually increased. In patients with liver impairment, the daily dose of telmisartan should not exceed 40 mg. For elderly patients (75 years and older), treatment should start at a lower dose.
Child dose
The safety and efficacy in pediatric patients under the age of 18 have not been established, thus the use of this medication is not recommended.

Ingredients

Manufacturer
(주)동구바이오제약

Efficacy & effects

Improvement in blood pressure control for essential hypertension

  • Essential hypertension
View approved original text

This medication helps effectively lower blood pressure in patients with essential hypertension who are not sufficiently controlled with monotherapy using amlodipine or telmisartan. It stabilizes blood pressure, reducing the risk of cardiovascular diseases. The combination therapy of both medications complements each other’s effects, making it effective for blood pressure management. It is used for the treatment of essential hypertension and improves blood pressure control according to the patient's condition.

How to take

Adult dose

The recommended dose is 1 tablet once daily, taken with water regardless of meals. It is advised to take it at the same time daily (e.g., morning). In patients with severe renal impairment, treatment should begin at a lower dose and be gradually increased. In patients with liver impairment, the daily dose of telmisartan should not exceed 40 mg. For elderly patients (75 years and older), treatment should start at a lower dose.

Child dose

The safety and efficacy in pediatric patients under the age of 18 have not been established, thus the use of this medication is not recommended.

Precautions

This medication can pose a serious risk to the fetus and newborn if taken during pregnancy, especially in the second and third trimesters, so it should not be taken by women who are pregnant or may become pregnant. Additionally, individuals allergic to any of the components of this medication, nursing women, and patients with severe liver disease or heart-related issues should not take this medication. Special caution is required when using this medication in patients with primary aldosteronism or certain heart valve diseases, and those with poor liver function. Patients with gastrointestinal diseases or kidney function problems should also be cautious when taking this medication. Possible side effects may include dizziness, swelling, decreased blood pressure, and more severe adverse reactions may occur rarely. Patients should be particularly cautious if blood pressure drops too low or if they have diminished heart function, and should consult a healthcare professional immediately if severe side effects occur. This medication may interact with other drugs, so inform healthcare providers about any other medications being taken. If pregnant or breastfeeding, it is essential to stop taking this medication and seek alternative treatment options. Older adults may need dosage adjustments, thus following medical advice is recommended. Overdose may lead to hypotension, dizziness, and cardiac issues, requiring immediate emergency treatment. This medication is not recommended for children as safety and efficacy have not been sufficiently established.

Side effects and when to seek care immediately

Serious side effects

Urticaria, angioedema (may result in fatal outcomes), Stevens-Johnson syndrome, exfoliative dermatitis, erythema multiforme, anaphylactic reactions, sepsis (including fatal outcomes), renal dysfunction (including acute kidney injury), hepatitis, jaundice, increased liver enzymes (often with cholestasis), myocardial infarction, ventricular tachycardia, arrhythmia, atrial fibrillation, vasculitis, dyspnea, intestinal angioedema, syncope, extrapyramidal disorders, muscle rigidity, peripheral neuropathy, severe swelling

Mild side effects

  • Dizziness
  • peripheral edema
  • fainting
  • drowsiness
  • headache
  • mood changes
  • depression
  • anxiety
  • insomnia
  • migraine
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  • paresthesia
  • taste abnormalities
  • tremors
  • vision impairment
  • vertigo
  • tinnitus
  • palpitations
  • bradycardia
  • tachycardia
  • flushing
  • hypotension
  • orthostatic hypotension
  • cough
  • abdominal pain
  • indigestion
  • nausea
  • vomiting
  • dry mouth
  • itching
  • sweating
  • rash
  • hair loss
  • purpura
  • skin discoloration
  • eczema
  • erythema
  • thrombocytopenia
  • increased serum creatinine
  • increased blood uric acid

Not everyone experiences these, and they can vary from person to person.

Storage

This medication is sensitive to light and should be stored in a container that protects it from light. It is best stored at room temperature between 1 to 30 degrees Celsius. Proper storage will help maintain the medication's effectiveness for a longer time.

Appearance and packaging

Appearance

Biconvex oval double tablet with one side white and the other side pale blue

Package unit

30 tablets/box [10 tablets/Alu-Alu X 3]

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

Questions about this medicine

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For anything that needs medical judgment, consult a doctor or pharmacist.

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.