Solinasin Tablet 5 mg (Solifenacin Succinate)

Adult dose

The usual recommended dose for adults (including older adults) is 5mg once daily. If necessary, the dose may be increased to a maximum of 10mg once daily. This medicine may be taken with or without food and should be swallowed whole with water. 1. Patients with renal impairment No dose adjustment is necessary in patients with mild or moderate renal impairment (creatinine clearance>30ml/min). Use with caution in patients with severe renal impairment (creatinine clearance≤30ml/min), and do not exceed 5mg once daily. 2. Patients with hepatic impairment No dose adjustment is necessary in patients with mild hepatic impairment. Use with caution in patients with moderate hepatic impairment (Child-Pugh class B), and do not exceed 5mg once daily. 3. Patients taking a strong cytochrome P450 3A4(CYP3A4) inhibitor For patients taking ketoconazole or another strong CYP3A4 inhibitor (e.g., ritonavir, nelfinavir, itraconazole), limit the maximum daily dose to 5mg.

This medication is used to control hypersensitivity reactions of the bladder. This medication should not be administered to patients with urinary retention symptoms, serious gastrointestinal diseases, myasthenia gravis, or narrow-angle glaucoma. Additionally, it should not be given to patients with hypersensitivity to this medication or its ingredients, patients undergoing hemodialysis, or those with severe liver or kidney impairment. Caution should be exercised in patients at risk of urinary retention or those with gastrointestinal obstructive diseases or reduced gastrointestinal motility, patients with severe renal impairment or moderate liver impairment, and those using certain concomitant medications. Common side effects of this medication may include dry mouth, constipation, blurred vision, urinary retention, and dry eyes; severe adverse reactions, such as gastrointestinal obstruction, may occur at high doses. Discontinuation of treatment due to side effects may occur, especially as dry mouth is the most common reason. This medication may rarely cause severe allergic reactions such as angioedema or anaphylaxis. If such symptoms occur, discontinue use immediately and seek appropriate medical treatment. Caution is advised when driving or operating machinery, as drowsiness, fatigue, and blurred vision may affect performance. When combined with other anticholinergic medications, this medication may increase effectiveness or exacerbate side effects, so consult a professional when co-administering. It may also reduce the effectiveness of medications that promote gastrointestinal motility. This medication is metabolized in the liver; therefore, dosage adjustments may be needed when administered to patients with impaired liver function or those taking strong liver enzyme inhibitors. The safety for pregnant women has not been established, so caution is advised when administering to pregnant women. During breastfeeding, it is advisable to avoid use, as this medication may pass into breast milk. The safety and efficacy in children have not been confirmed, so this medication should not be administered to children. In cases of overdose, central nervous system symptoms, blurred vision, and dizziness may occur, and gastric lavage and detoxification treatment may be necessary. Patients with QT prolongation syndrome or heart disease should exercise special caution as cardiac rhythm irregularities may occur with this medication.

• Dry mouth
• constipation
• blurred vision
• urinary retention
• dry eyes
• fecal impaction
• colonic obstruction
• intestinal obstruction
• angioedema
• nausea

This medication should be stored in a tightly closed container to prevent air or moisture from entering, and it is best to keep it at room temperature between 1 and 30 degrees Celsius. By storing it this way, the efficacy of the medication can be maintained and deterioration prevented.

Appearance

Bright yellow round film-coated tablet

Package unit

30 tablets (10 tablets/PTP X 3)