Melinjies Capsule (Tranexamic Acid)

Adult dose

As tranexamic acid, the usual adult dose is divided into 3 to 4 oral doses of 750 to 2000 mg per day. Adjustments should be made according to age and symptoms.

This medication should not be used in patients receiving thrombin. It should be avoided in patients with severe renal impairment due to the risk of drug accumulation in the body. Patients with allergic reactions to this drug or its components are prohibited from using it. This drug should not be administered to patients with active thromboembolism. Patients with thrombosis or at risk of thrombosis should use this drug cautiously, as it may stabilize existing thrombosis. Patients with consumption coagulopathy should be careful when using this drug in combination with other blood coagulation-related medications. Patients who are bedridden for a long time after surgery or receiving compressive hemostatic treatment are at risk of venous thrombosis, and the risk of thrombosis may increase with this drug. Patients with reduced kidney function should be cautious as the drug concentration may increase in their bloodstream. This medication contains the dye Tartrazine (Yellow No. 5), so patients who are allergic or sensitive to this component should use it with caution. This drug can rarely cause shock reactions, so if abnormal symptoms occur during use, the medication should be discontinued immediately and appropriate treatment sought. If allergy symptoms such as itching, rash, or facial flushing occur, the medication should also be discontinued and treatment sought. The ability to distinguish colors may temporarily change, and if such symptoms occur, the use of the medication should be stopped. In patients who develop hematuria in the upper urinary tract, caution is needed as ureteral obstruction may occur with this medication. Occasionally, gastrointestinal symptoms such as loss of appetite, nausea, vomiting, diarrhea, and dyspepsia may occur. Rarely, drowsiness or headache may occur, and intravascular thrombosis or thromboembolism has been reported. Patients with hereditary angioedema should have regular eye examinations and liver function tests if taking this medication long-term. Patients with abnormal menstrual bleeding should not use this drug until the cause of bleeding is clearly determined, and if bleeding does not decrease, other treatment options should be considered. This drug can increase the risk of thrombosis when used with other medications that promote thrombosis, so it is advisable not to combine them. When using this drug in conjunction with other medications affecting blood coagulation, careful administration is necessary. Patients taking hormonal contraceptives may have an increased risk of thromboembolism, so non-hormonal methods of contraception are recommended if using this medication. Pregnant women should use it cautiously as it can cross the placenta, and breastfeeding women should be aware that a small amount may be transferred to breast milk, though it is believed to have no significant effect on infants. Caution is necessary when using in children under 15 years of age due to insufficient experience. Elderly patients may have decreased physical function, so careful use with dosage adjustments is necessary. In cases of overdose, symptoms such as nausea, vomiting, and orthostatic hypotension may occur, and immediate measures such as inducing vomiting, gastric lavage, or administering activated charcoal should be undertaken, considering anticoagulant therapy if there is a risk of thrombosis. Caution is needed as prolonged high-dose administration may lead to retinal changes.

Serious side effects

Shock, thrombosis and thromboembolism, ureteral obstruction due to massive hematuria

Mild side effects

Itching, rash, flushing of the skin, temporary disturbances in color perception, loss of appetite, nausea, vomiting, diarrhea, dyspepsia, drowsiness, headache, orthostatic hypotension

This medication should be stored in a tightly sealed container to prevent air entry, and it is best to keep it at room temperature between 1 and 30 degrees Celsius. Storing it this way helps maintain the drug's effectiveness and prevents deterioration.

Appearance

Hard capsule with orange upper part and yellowish lower part containing white powder

Package unit

30 capsules/bottle, 100 capsules/bottle