Telmutwin Tablet 40/10 mg

Adult dose

The recommended dosage for this medication is one tablet once daily, taken with water regardless of meals. It is advised to take it at the same time every day (e.g., in the morning) if possible. For patients with kidney impairment, dosage adjustment is not needed for mild and moderate kidney impairment; however, for severe kidney impairment, treatment should begin at a lower dose and gradually increase. Patients with liver impairment should not exceed a daily dose of 40 mg.

Child dose

Safety and efficacy in pediatric patients under 18 years have not been established, and the use of this medication is not recommended in this population.

This medication can pose serious risks to the fetus and newborn during pregnancy, particularly in the second and third trimesters, and should not be taken by pregnant women or women who may become pregnant. This medication is contraindicated in patients with certain conditions. For instance, individuals with allergies to this medication's components, biliary obstruction diseases, severe liver dysfunction, severe hypotension, cardiogenic shock, or unstable heart failure following acute myocardial infarction should not use it. Furthermore, patients with primary aldosteronism, aortic or mitral stenosis, obstructive hypertrophic cardiomyopathy, liver disorders, gastrointestinal diseases, renal artery hypertension, dialysis patients, and the elderly should use this medication cautiously. The most common side effects when taking this medication include dizziness and peripheral edema, and serious side effects, such as fainting, may rarely occur. If side effects are experienced, medical consultation should be sought immediately. The use of this medication should be avoided during pregnancy, and if pregnancy is confirmed, discontinuation should occur as soon as possible and substituted with other safe treatments. Due to the risk of hypotension, patients with insufficient fluid or salt should correct their condition before taking this medication, and if hypotensive symptoms arise, appropriate actions should be taken. As blood potassium levels may increase, caution should be exercised when taking potassium supplements or potassium-rich foods, and regular monitoring of serum potassium and renal function is advised. Patients with compromised kidney function should frequently monitor their renal function and electrolyte levels while taking this medication. For patients with cardiovascular diseases, caution is warranted due to the potential worsening of myocardial infarction or angina from blood pressure reduction. This medication may cause drowsiness or dizziness; therefore, caution should be exercised while driving or operating hazardous machinery. There may be interactions with other medications, particularly when co-administered with digoxin, lithium, warfarin, non-steroidal anti-inflammatory drugs, or grapefruit juice; medical consultation should be performed in such cases. It is advisable for breastfeeding women not to take this medication. Safety and efficacy in pediatric patients have not been sufficiently established; hence, use in this population is not recommended. Although this medication can be administered to elderly patients without dosage adjustment, caution is necessary as they may respond more sensitively. In case of overdose, symptoms such as hypotension, tachycardia, dizziness, and acute renal failure may occur, so immediate medical attention is required. This medication should be kept out of the reach of children and not transferred to other containers to maintain quality. It should be stored sealed until administration, and it is best to open the packaging just before taking it.

Serious side effects

Hives, severe swelling (angioedema), chest tightness, difficulty breathing, cold sweat, pallor, severe rash accompanied by high fever, blisters, skin peeling, mucosal pain in the mouth/eyes, shortness of breath or difficulty breathing, asthma attacks, respiratory distress accompanied by cough and fever, yellowing of the skin or eyes (jaundice), extreme fatigue, sudden and severe headache, thunderclap headache, seizures, confusion, visual disturbances, paralysis.

Mild side effects

• Dizziness
• peripheral edema
• upper respiratory tract infection
• urinary tract infection
• anemia
• hyperkalemia
• hypoglycemia
• depression
• insomnia
• drowsiness

This medication must be stored in a tightly sealed container that blocks light, and the storage temperature should be maintained at room temperature between 1 and 30 degrees Celsius. This storage method will safely preserve the effectiveness of the medication.

Appearance

This double tablet is oval-shaped and convex on both sides, with a white and light gray color.

Package unit

30 tablets (10 tablets/PTP X 3)