Ethyve Tablet (Ezetimibe)

Adult dosage

The recommended dosage of this medication is 10 mg once daily and should be taken regardless of meals. When combined with HMG-CoA reductase inhibitors for primary hypercholesterolemia patients, treatment may begin with this medication at the recommended initial doses of HMG-CoA reductase inhibitors, and if already receiving high doses of HMG-CoA reductase inhibitors, the dose of HMG-CoA reductase inhibitors should be maintained while this medication is co-administered.

This medication should not be used by patients who have allergies to specific components. Patients with active liver disease or persistently elevated liver enzyme levels should not use this medication along with certain lipid-lowering agents. Pregnant or breastfeeding women should exercise caution as the combination of this medication with some lipid-lowering agents is prohibited. Patients with severe liver dysfunction, gallbladder disease, or severe renal impairment should not use this medication with certain lipid-lowering agents. This medication should not be administered to patients with lactose intolerance or metabolic disorders. The use of this medication is not recommended for patients with moderate to severe liver dysfunction, and regular liver function tests should be performed. Generally, this medication is well-tolerated; however, side effects such as headache, abdominal pain, diarrhea, and muscle pain may occur, and if any unusual symptoms arise, consulting a doctor is advised. The risk of muscle-related side effects may slightly increase when using this medication with certain statin drugs, so immediate reporting of muscle pain or weakness is necessary. Patients with impaired renal function may use this medication, but caution is required in cases of severe renal impairment, and dose adjustments may not be necessary in some situations. There may be interactions with other medications, especially when used in combination with cholestyramine, fibrates, cyclosporine, anticoagulants, etc., so consultation with a doctor is necessary. It is safe not to use this medication during pregnancy or breastfeeding, and women of childbearing age are advised to use appropriate contraception. This medication is not recommended for children under 6 years old, and for those over 6 years old, pharmacokinetic characteristics are similar to adults. Elderly individuals may use this medication, but some may be more sensitive to it, so caution is advised. In the case of overdose, there is no specific antidote available, and appropriate treatment should be administered based on symptoms. This medication should be kept out of reach of children and should not be transferred to other containers.

Serious side effects

Hives, severe swelling (edema), anaphylaxis, allergic reactions including rash and angioedema, Stevens-Johnson syndrome, toxic epidermal necrolysis, drug reaction with eosinophilia and systemic symptoms (DRESS), severe skin reactions including erythema multiforme, drug-induced liver injury, hepatitis, pancreatitis, renal failure (kidney disease), headache (possible severe neurological symptoms)

Mild side effects

• Fatigue
• abdominal pain
• diarrhea
• viral infection
• pharyngitis
• sinusitis
• joint pain
• lower back pain
• cough
• chest pain

This medication should be stored in a tightly closed container to protect it from air and moisture. Also, do not store the medication in excessively hot or cold places; it is recommended to keep it at room temperature between 1°C and 30°C.

Appearance

White to almost white oblong tablet

Package unit

30 tablets (10 tablets/PTPX3)