Genewon Ezetimibe Tablet 10 mg (Ezetimibe)

Adult dosage

The recommended dosage for this medication is 10 mg once daily and may be taken regardless of meals. When administered in combination with HMG-CoA reductase inhibitors, start this medication at the recommended initial dosage for the HMG-CoA reductase inhibitor, and if the patient is already on a high dose of the HMG-CoA reductase inhibitor, continue the current dosage while adding this medication.

This medication should not be used in patients who are allergic to certain components. Patients with liver diseases or persistently elevated liver enzyme levels should not take this medication in combination with certain lipid-lowering agents. Pregnant or breastfeeding women should avoid concomitant use of this medication with specific lipid-lowering agents, hence caution is required. Patients with moderate to severe liver dysfunction may experience increased exposure to this medication, resulting in unexpected side effects; therefore, it is not recommended. This medication contains lactose and should not be administered to patients with lactose intolerance or related genetic conditions. Patients experiencing muscle pain, muscle weakness, or unexplained fatigue during treatment should immediately inform healthcare professionals, and in severe cases, discontinuation may be necessary. Periodic liver function tests may be required to monitor liver function. Caution is warranted when this medication is used in combination with other lipid-lowering agents due to the increased risk of liver enzyme elevation and muscle-related side effects. Patients with severe renal impairment should also be cautious during administration, and dosage adjustments may be necessary. In children, it is not recommended for those under six years old, and should only be used from six years of age if safety and efficacy have been confirmed. Elderly patients are generally safe but should be observed closely as some may be more sensitive to the medication. During treatment with this medication, there is potential for drug interactions; patients must inform their healthcare professional of any other medications currently in use. In the case of overdose, there is no specific antidote and symptomatic treatment will be provided. This medication should be stored out of reach of children and should not be transferred to other containers.

Serious side effects

Urticaria, severe swelling (edema), anaphylaxis, hypersensitivity reactions including rash and angioedema, mucocutaneous syndrome (Stevens-Johnson syndrome), toxic epidermal necrolysis (Lyell's syndrome), eosinophilia with systemic symptoms drug reaction (DRESS), severe skin reactions including polymorphic erythema (SCARs), drug-induced liver injury, renal failure (kidney disease), liver dysfunction, rhabdomyolysis, myopathy, amino transferases elevation

Mild side effects

• Fatigue
• abdominal pain
• diarrhea
• viral infections
• pharyngitis
• sinusitis
• arthralgia
• low back pain
• cough
• dizziness

This medication should be stored in a tightly closed container to protect it from air and moisture. The safest and most effective storage temperature is between 1°C and 30°C.

Appearance

White to almost white oblong tablets

Package unit

30 tablets (10 tablets/PTP x 3)