Lexpazique Tablet 5/80 mg

Adult dose

The recommended dosage is 1 tablet per day, taken with water regardless of meals. It is advised to take it at the same time daily (e.g., in the morning). Dosage adjustment and switching methods are as follows. ㆍ 5/80 mg: Given to patients whose blood pressure is not controlled by amlodipine 5 mg or valsartan 80 mg monotherapy. ㆍ 5/160 mg: Given to patients

Child dose

The safety and efficacy of this medication in pediatric patients under 18 years have not been established, so its use is not recommended.

This medication can cause serious harm to the fetus if taken during pregnancy, especially in the second and third trimesters; therefore, it should be stopped immediately if pregnancy is confirmed. This medication is contraindicated in individuals with allergies to any of the ingredients, women who are pregnant or nursing, patients with severe kidney or liver dysfunction, and those with certain heart diseases. Patients with insufficient sodium or body fluids should improve their condition before taking this medication and closely monitor their blood pressure and symptoms during treatment. Patients with high potassium levels must frequently check their potassium levels when taking this medication alongside potassium supplements or medications that increase potassium. Patients with kidney issues or those who have undergone kidney transplants should closely monitor changes in kidney function while taking this medication. This medication may cause a serious allergic reaction called angioedema; therefore, if swelling occurs in the face, lips, or tongue, or if breathing difficulties arise, the medication should be stopped immediately, and medical advice sought. Patients with heart failure or after myocardial infarction should periodically check their renal function and blood pressure while taking this medication, and some heart disease patients require caution when taking it. The risk of hypotension, hyperkalemia, and worsening renal function may increase when this medication is used with other antihypertensives; therefore, it should be taken according to healthcare provider instructions. Dizziness, drowsiness, and headaches may occur during treatment, so caution is advised when driving or operating machinery. Overdosing on this medication may lead to severe hypotension or cardiac problems; thus, the dosage must be strictly adhered to and immediate medical attention sought in case of an overdose. Nursing mothers are advised to avoid taking this medication, and its safety has not been adequately established in pediatric patients, hence it is not recommended for them. Elderly patients may take similar dosages as regular adults, but they should be cautious regarding the possibility of side effects.

Serious side effects

Hives, severe swelling (edema), chest tightness, difficulty breathing, cold sweat, pallor, severe rash with fever, blisters, peeling skin, pain in oral/ocular mucosa, shortness of breath or difficulty breathing, asthma attack, respiratory distress accompanied by cough and fever, yellowing of skin or eyes (jaundice), extreme fatigue, sudden and severe headache, lightning-like headache, seizures, confusion, visual disturbances, paralysis, urination abnormalities

Mild side effects

• Nasopharyngitis
• influenza
• anxiety
• headache
• dizziness
• drowsiness
• orthostatic dizziness
• sensory abnormalities
• vertigo
• tinnitus

This medication should be stored in a tightly sealed container to prevent exposure to air or moisture. The recommended storage temperature is between 1 and 30 degrees Celsius, at room temperature.

Appearance

Dark yellow round film-coated tablet

Package unit

28 tablets (14 tablets/Alu-Alu X 2), 30 tablets (bottle)