Dobe Tablets 250 mg (Calcium Dobesilate Hydrate)

Adult dose

Adults: Administer the following doses of calcium dobesilate hydrate orally. 1. Vascular damage and retinopathy: 500~1000mg daily 2. Venous disease: Administer 750mg daily for 1~3 weeks, then administer 500mg daily. Administer after meals with plenty of fluids. Adjust the dose as appropriate according to age and symptoms.

This medication should not be used by individuals who are allergic to this medication or any of its ingredients. This drug contains lactose, so individuals with hereditary lactose intolerance, certain enzyme deficiencies, or glucose-galactose malabsorption should avoid taking it. Caution is required for patients with impaired kidney function. Since this drug is excreted by the kidneys, doses should be reduced or used with caution in patients with renal failure. Caution is also needed for patients with poor liver function, and if liver enzyme levels increase, the treatment effects and side effects should be re-evaluated. This drug contains sulfites, which may cause allergic reactions or asthma attacks in individuals who are allergic to sulfites, so caution is advised. During treatment, symptoms such as headache, abdominal pain, nausea, diarrhea, vomiting, joint pain, and muscle pain may occur, and liver enzyme levels may also rise due to liver dysfunction. Rarely, serious side effects such as a decrease in blood cell counts may occur, so if high fever or signs of infection appear, consult a physician immediately. If an allergic reaction occurs, discontinue the drug immediately and inform healthcare personnel. The effects on driving or operating machinery are not known, so caution is necessary. It is advisable to avoid using this medication during pregnancy or breastfeeding, particularly during breastfeeding, it is recommended to either discontinue the medication or stop breastfeeding. Safety in pediatric patients has not been adequately studied, so caution should be exercised when administering to children. This medication may affect blood test results, therefore it is advisable to collect the test samples prior to administration. No specific symptoms are reported regarding overdose, however, general emergency measures should be taken.

• Agranulocytosis
• neutropenia
• leukopenia
• skin rash
• allergic dermatitis
• itching
• urticaria
• facial edema
• anaphylactic reaction
• headache

This medication may be sensitive to air and moisture, so it should be kept in a tightly closed container. It is advisable to maintain the storage temperature between 1 and 30 degrees Celsius to preserve the medication's effectiveness for a longer duration.

Appearance

White oval tablet

Package unit

10 tablets/bottle, 30 tablets/bottle, 90 tablets/bottle, 300 tablets/bottle