Rosen Soft Capsule (Naproxen)

Adult dose

1. Rheumatoid Arthritis, Osteoarthritis, Ankylosing Spondylitis Administer 250–500 mg of naproxen orally, twice daily (every 12 hours). 2. Acute Gout As an initial dose, administer 750 mg orally, then give 250 mg orally every 8 hours until the attack resolves. 3. Skeletal Muscle Disorders, Postoperative Pain, Pain After Tooth Extraction, Dysmenorrhea, Tendinitis, Bursitis Start with an initial dose of 500 mg administered orally, then follow up with 250 mg every 6–8 hours.

This medication may pose a risk of gastrointestinal bleeding if taken by individuals who regularly consume more than three drinks per day; it is essential to consult a physician or pharmacist. Use with caution as it may increase the risk of cardiovascular diseases; individuals with a history or risk factors for heart disease or stroke should take special care. Serious issues such as gastrointestinal bleeding, ulcers, or perforations may occur, so elderly patients or those with a history of gastrointestinal diseases should monitor symptoms closely while taking this medication. It is safer not to use this medication if there are histories of peptic ulcers, severe blood abnormalities, liver dysfunction, heart failure, kidney disorders, or hypertension. Patients with specific conditions such as a history of peptic ulcers, blood abnormalities, liver or kidney diseases, hypertension, asthma, the elderly, or drug hypersensitivity should be more cautious while taking this medication. Hypersensitivity reactions such as difficulty breathing, skin rashes, or hives may occur; if these symptoms appear, stop taking the medication immediately and consult medical personnel. Gastrointestinal symptoms such as hematemesis, gastrointestinal bleeding, abdominal pain, nausea, and diarrhea may occur; any abnormal symptoms should be discussed with a physician immediately. Various side effects such as blood disorders, liver dysfunction, kidney dysfunction, mental disturbances, and skin reactions have been reported; regular check-ups may be necessary. This medication may interact with other non-steroidal anti-inflammatory drugs or specific medications, so inform your doctor about any other drugs you are taking. It should be avoided during pregnancy, particularly in the third trimester, as it may pose risks to the fetus, and it is also advisable not to take this medication while breastfeeding as it may affect the baby through breast milk. Caution is recommended for children, particularly infants under 2 years of age, as safety has not been established, and elderly patients should start with lower doses due to a higher risk of side effects. Overdose may lead to symptoms like drowsiness, dyspepsia, and vomiting; if an overdose is suspected, contact a healthcare facility for appropriate measures immediately. Store this medication in a safe place out of reach of children, and do not transfer it to other containers as this is important for maintaining quality and safety.

Serious side effects

• Hives
• severe swelling (edema)
• chest tightness
• difficulty breathing
• cold sweats
• hypotension
• respiratory distress
• wheezing
• asthma attacks
• hematemesis

Mild side effects

Itching, rash, unpleasant sensation in the upper abdomen, abdominal pain, nausea, vomiting, loss of appetite, dyspepsia, heartburn, diarrhea, constipation, stomatitis, abdominal bloating, melena, thirst, agranulocytosis, eosinophilia, leukopenia, thrombocytopenia, aplastic anemia, hemolytic anemia, impaired platelet function, elevated GOT, GPT, hepatitis, kidney disorders, glomerulonephritis, hematuria, hyperkalemia, interstitial nephritis, nephrotic syndrome, renal papillary necrosis, proteinuria

Drug interactions

Do not take this medication with other non-steroidal anti-inflammatory drugs (NSAIDs) and naproxen derivatives, aspirin, high doses of methotrexate, hydantoins, sulfonamides, sulfonylurea-based hypoglycemic agents, propranolol, and other beta-blockers, ACE inhibitors (such as captopril), loop diuretics, thiazide diuretics, probenecid, lithium, low-dose methotrexate, or coumarin anticoagulants.

This medication should be stored in an airtight container to prevent air from entering and is best kept at room temperature between 1 and 30 degrees Celsius. Proper storage helps maintain the medication's effectiveness and safety.

Appearance

Transparent green oval soft capsules containing a colorless, transparent liquid

Package unit

10 capsules / PTP