Medication info
Retium Tablets (Dovesil Acid Calcium Hydrate)

Retium Tablets (Dovesil Acid Calcium Hydrate)

Prescription medicationTabletOral
Ingredient · strength
Dobesilate Calcium Hydrate›250mg / 1 tablet
Manufacturer / importer
International Pharmaceutical Co., Ltd.
Appearance
White rectangular tablets
Packaging
90 tablets (10 tablets/PTP × 9), 120 tablets (10 tablets/PTP × 12)
Approval status
Active

MFDS item code 201700355 · Approved 2017.01.18 · Insurance code 643704420

Summary

Main use
Treatment of vascular injury and capillary disorders, venous disorders (such as congestive edema), and hemorrhoids
Who takes it
Adults
Adult dose
Adults: Administer the following doses orally, as calcium dobesilate hydrate. 1. Vascular damage and retinopathy: 500-1000mg daily 2. Venous disease: Administer 750mg daily for 1-3 weeks, then administer 500mg daily. Take after meals with plenty of fluids. The dose may be adjusted according to age and symptoms.

Ingredients

Manufacturer
International Pharmaceutical Co., Ltd.

Efficacy & effects

Treatment of vascular injury and capillary disorders, venous disorders (such as congestive edema), and hemorrhoids

  • Exaggerated capillary rupture
  • permeability disorder
  • vascular damage
  • diabetic microangiopathy
  • diabetic retinopathy
  • venous insufficiency
  • post-thrombotic syndrome
  • peripheral venous edema
  • hemorrhoids
View approved original text

This medication helps improve vascular damage, capillary rupture, and permeability disorders. It is particularly effective in treating capillary disorders and retinopathy due to diabetes. It is also used for venous insufficiency caused by decreased venous function and post-thrombotic syndrome. Additionally, it helps alleviate symptoms of peripheral venous edema and hemorrhoids. Overall, it is used to improve vascular health and alleviate related symptoms.

How to take

Adult dose

Adults: Administer the following doses orally, as calcium dobesilate hydrate. 1. Vascular damage and retinopathy: 500-1000mg daily 2. Venous disease: Administer 750mg daily for 1-3 weeks, then administer 500mg daily. Take after meals with plenty of fluids. The dose may be adjusted according to age and symptoms.

Precautions

This medication should not be used by individuals who are allergic to this drug or its components. Caution is required when used in patients with poor renal function. This drug is excreted through the kidneys, so the dosage may need to be reduced in patients with severely impaired renal function. Caution is also necessary for patients with impaired liver function. If liver function deteriorates, liver enzyme levels may rise, and in such cases, the benefits and risks of treatment should be reassessed. This medication contains sodium bisulfite, which may cause allergic reactions or asthma attacks in individuals allergic to sulfites, so caution is advised. Rarely, this medication may cause abnormalities in the blood. If there are symptoms such as high fever or signs of infection, the patient should immediately inform a physician, and blood tests should be conducted to check the condition. Furthermore, if hypersensitivity reactions such as skin rashes, itching, hives, or facial swelling occur, the patient should stop taking the drug immediately and seek medical attention. Common side effects may include headache, abdominal pain, nausea, diarrhea, vomiting, joint pain, muscle pain, fever, chills, lethargy, and fatigue. If these symptoms are severe, the dosage may need to be reduced or the medication temporarily stopped. The effects on driving or machine operation are unclear, so caution is needed. Women who are pregnant or breastfeeding are advised not to use this medication; especially during breastfeeding, the drug should be discontinued or breastfeeding stopped. The safety and efficacy of this medication have not been sufficiently studied in children, so its use is not recommended. There are no specific precautions for elderly patients over 65, but they should always take the medication according to their physician's instructions. This medication may affect certain blood test results, so it is advisable to conduct tests before starting the medication.

Side effects

  • Agranulocytosis
  • neutropenia
  • leukopenia
  • skin rash
  • allergic dermatitis
  • itching
  • urticaria
  • facial edema
  • anaphylactic reaction
  • headache
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  • abdominal pain
  • nausea
  • diarrhea
  • vomiting
  • elevated alanine aminotransferase
  • arthralgia
  • myalgia
  • fever
  • chills
  • lethargy
  • fatigue

Not everyone experiences these, and they can vary from person to person.

Storage

This medication may be sensitive to air and moisture, so it should be stored in a tightly sealed container. It is advisable to maintain a storage temperature between 1 and 30 degrees Celsius to safely preserve the medication's effectiveness for a long time.

Appearance and packaging

Appearance

White rectangular tablets

Package unit

90 tablets (10 tablets/PTP × 9), 120 tablets (10 tablets/PTP × 12)

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

Questions about this medicine

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.