Medication info

Pobiwon Injection (Thiamine Hydrochloride)

Prescription medication
Ingredient · strength
Fursultiamine Hydrochloride›5.46mg / 1mL
Manufacturer / importer
(주)테라젠이텍스
Appearance
This medication is a colorless, odorless liquid with a slightly bitter taste, filled in a brown ampoule containing a clear liquid.
Packaging
10 ampoules/box [10 milliliters/ampoule × 10]
Approval status
Active

MFDS item code 201700028 · Notified 2017.01.03

Summary

Main use
Improvement of neuralgia, myalgia, etc. caused by vitamin B1 deficiency and metabolic disorders
Who uses it
Adults
Adult dosage
For thiamine, the typical dosage for adults is subcutaneously, intramuscularly, or intravenously 5 – 100 mg daily. Adjust as appropriate based on symptoms.

Ingredients

Manufacturer
(주)테라젠이텍스

Efficacy & effects

Improvement of neuralgia, myalgia, etc. caused by vitamin B1 deficiency and metabolic disorders

  • Vitamin B1 deficiency
  • Wernicke's encephalopathy
  • beriberi heart disease
  • neuralgia
  • myalgia
  • arthralgia
  • peripheral neuritis
  • peripheral nerve paralysis
  • myocardial metabolic disturbances
  • constipation
  • gastrointestinal motility dysfunction
  • intestinal paralysis
View approved original text

This medication is used for the prevention and treatment of vitamin B1 deficiency. It acts as a supplement especially when food intake is insufficient, for instance in cases of hyperthyroidism, pregnancy and lactation, or intense physical labor. Additionally, it assists in the treatment of severe neurological and cardiac conditions such as Wernicke's encephalopathy and beriberi heart disease. This medication may also be effective for symptoms such as neuralgia, myalgia, peripheral neuritis, myocardial metabolic disorders, and gastrointestinal motility disorders associated with suspected vitamin B1 deficiency or metabolic disorders. However, it is important not to use it aimlessly for more than one month. This medication is used to improve and treat various symptoms related to vitamin B1 deficiency.

Dosage and Administration

Adult dosage

For thiamine, the typical dosage for adults is subcutaneously, intramuscularly, or intravenously 5 – 100 mg daily. Adjust as appropriate based on symptoms.

Precautions

This medication is administered via injection, and caution must be exercised as glass fragments may be present when cutting the injection container. Especially when used in children or the elderly, extra care is necessary. Patients who have had allergies to this medication or its components should not use it. Patients with allergies should also use it with caution. Although rare, severe allergic reactions may lead to shock; if symptoms such as blood pressure drop, chest pain, or respiratory distress occur, administration should be stopped immediately and appropriate treatment should be sought. Additionally, side effects such as rash, nausea, vomiting, stomatitis, diarrhea, headache, and frequent urination may occur, and it is advisable to consult a doctor if symptoms arise. Injections should be administered slowly as much as possible to reduce vascular pain. To prevent bacterial contamination, unused solution should not be reused. When cutting the ampoule, the marked part should be facing upwards, and the opposite side should be cut carefully. To prevent foreign substances, the top of the ampoule should be cleaned with an alcohol swab. This medication should be stored in a safe place out of the reach of children, and care should be taken not to transfer it to another container as it may pose a risk of accidents and degrade the quality of the medication.

Side effects and when to seek care immediately

Serious side effects

  • Shock
  • blood pressure drop
  • chest pain
  • respiratory distress

Mild side effects

  • Nausea
  • vomiting
  • stomatitis
  • diarrhea
  • headache
  • frequent urination
  • vascular pain
  • rash

Not everyone experiences these, and they can vary from person to person.

Storage

This medication should be stored in an opaque container to prevent exposure to light, and it is advisable to keep it at room temperature between 1 and 30 degrees Celsius. Proper storage will help maintain the efficacy of the medication and prevent deterioration.

Appearance and packaging

Appearance

This medication is a colorless, odorless liquid with a slightly bitter taste, filled in a brown ampoule containing a clear liquid.

Package unit

10 ampoules/box [10 milliliters/ampoule × 10]

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.