Prohylon Injection (Sodium Hyaluronate) (Pre-filled)

Adult administration

For cataract surgery and intraocular lens implantation, the required amount is slowly injected into the anterior chamber before or after lens removal using a needle or cannula. It should be administered before intraocular and capsule cataract surgery. During corneal transplant surgery, fill the anterior chamber with this medication until the corneal graft surface level matches, and place the donor graft on top before suturing. In glaucoma filtration surgery, it is injected through corneal puncture to supplement and maintain anterior chamber volume.

This medication is an ophthalmic injection containing sodium hyaluronate as the main ingredient, used during eye surgery. First, this medication should not be administered to patients who have had allergic reactions to any components or proteins from pharmaceutical products. There can be various side effects when using this medication, such as increased intraocular pressure or inflammation in the eyes. Additionally, corneal edema or opacification, bleeding, abnormality in the iris can occur, and symptoms such as eye pain, itching, and decrease in vision may arise. Also, due to the phosphate component in this medication, in rare cases, corneal calcification may occur in patients with severely damaged corneas, so caution is necessary. Post-surgery, it is particularly important to meticulously check the intraocular pressure, and if there is an increase, appropriate treatment should be received. It is also advisable to remove this medication as much as possible through irrigation or aspiration after surgery. When performing ultrasound emulsification during surgery, sufficient irrigation fluid should be allowed to flow between the lens and this medication through the aspiration system. When cleaning surgical instruments, solutions containing quaternary ammonium compounds such as benzalkonium chloride should not be used. This medication contains components derived from avian cells, which may trigger immune responses or other risks, so appropriate caution is required. Additionally, it should not be used in conjunction with the drug hyaluronidase. When administering, it is essential to adhere strictly to the prescribed methods and dosages for ophthalmic use, and it must never be injected intravenously. Before usage, the refrigerated medication should be allowed to reach room temperature for approximately 30 minutes to obtain the proper temperature. Caution should be taken as mixing with benalkonium chloride or chlorhexidine may lead to the formation of precipitates. Once opened, the medication should be used once and any remaining product must be discarded along with its container. When using this medication mixed with air, care should be taken to ensure that air does not enter beneath the iris, and administration should be done slowly and cautiously. When injecting into the anterior chamber, care should be taken to avoid overdose, as an overdose may cause elevated intraocular pressure. Finally, this medication should be kept out of reach of children and stored in a cool, dry place, avoiding direct sunlight, preferably in a sealed container. Additionally, to prevent misuse and maintain quality, the medication should not be transferred to another container.

Mild side effects

Increased intraocular pressure, inflammatory reactions, corneal edema, corneal opacification, anterior bleeding, iris neovascularization, posterior iris ulcer, conjunctival adhesion deficiency, mydriasis, lens opacification, pain, itching, blurred vision, corneal dysfunction, opacification of the surface of the intraocular lens, corneal calcification.

This medication should be stored in a sealed container, maintaining a temperature between 2 degrees and 8 degrees. Keep away from direct sunlight in a cool place and avoid freezing.

Appearance

A colorless, transparent, viscous liquid contained within a glass vial sealed with rubber stoppers (part of the pre-filled syringe system).

Package unit

0.85mL/vial