Ambes Tablet (Amlodipine Besilate)

Adult dose

Adult: Administer 5 mg of amlodipine orally once daily, which can be increased to a maximum of 10 mg daily based on the patient's response. Adjust as appropriate according to age and symptoms.

This medication should not be used in certain patients. It is contraindicated in patients who have had an allergic reaction to this drug or similar drugs, breastfeeding women, patients with severe liver dysfunction, patients with severe aortic stenosis, and patients in a state of shock. Additionally, it should be used with caution in patients with severe hypotension, those requiring renal dialysis, the elderly, and pregnant or potentially pregnant women. This medication generally has few side effects, but symptoms such as flushing, fatigue, swelling, rapid heartbeat, dizziness, headache, drowsiness, abdominal pain, and nausea may occur. Rarely, low blood pressure, vasculitis, neurological symptoms, sexual dysfunction, dyspepsia, weight changes, skin rash, and liver dysfunction have been reported. It should be used with caution in patients with heart failure or liver dysfunction, as the drug may remain in the body for a long time, and the hypotensive effect may diminish slowly. Therefore, conditions should be monitored carefully even after discontinuation of the medication. This drug is known not to significantly affect the ability to drive or operate machinery. Additionally, there may be interactions when taken with other medications, so caution is needed, especially when used concurrently with specific antibiotics, antihypertensives, grapefruit juice, certain analgesics, or immunosuppressants. Safety during pregnancy has not been established, so it is advisable not to use it unless absolutely necessary, and it is recommended to discontinue breastfeeding when taking this drug. Use is recommended only for children aged 6 years and above, and safety and efficacy have not been established in children under 6 years. In case of overdose, blood pressure may drop severely and heartbeats may become irregular, so immediate medical assistance should be sought, and gastric lavage or detoxification may be necessary if required. Finally, there is no evidence that long-term use of this drug increases the risk of cancer or causes genetic abnormalities.

Serious side effects

• Hives
• severe swelling (edema)
• difficulty breathing
• yellowing of the skin or eyes (jaundice)
• hepatitis
• jaundice
• toxic epidermal necrolysis
• severe edema or urinary abnormalities.

Mild side effects

• Flushing
• fatigue
• swelling
• palpitations
• dizziness
• headache
• drowsiness
• abdominal pain
• nausea
• weakness

This medicine must be stored in a tightly sealed container to protect it from air and humidity. It is important to maintain a storage temperature between 1 and 30 degrees Celsius at room temperature.

Appearance

White octagonal tablet

Package unit

30 tablets/bottle, 300 tablets/bottle