D3 Base Oral Solution 25,000 IU/2.5 mL (Cholecalciferol)

Adult dose

Adults take one (25,000 IU) orally with meals once every month.

This drug contains Vitamin D, so it is important to check the total Vitamin D content when taking other medications or fortified foods that also contain Vitamin D to prevent overdose. Regular monitoring of calcium levels in the blood is required; if serum calcium exceeds 10.5 mg/dL or urinary calcium exceeds 4 mg/kg in adults within a day, this medication should be discontinued. If calcium intake is high, it is important to consistently monitor blood and urine calcium levels. This drug should not be used in specific patients, such as those allergic to it, those with high calcium levels, those with calcium stones in the kidneys, or those with impaired kidney function. Also, it should not be administered to immobile patients, patients with sarcoidosis, or patients with pseudohypoparathyroidism. While taking this drug, various adverse reactions may occur, including headache, fatigue, muscle pain, nausea, vomiting, diarrhea, increased thirst or urination, elevated blood pressure, calcium stones, kidney issues, arrhythmias, and mental symptoms, so caution is needed. In case of overdose, Vitamin D administration should be stopped, calcium intake should be reduced, fluid intake should be increased, and diuresis should be encouraged. Regular blood tests for 25-hydroxy Vitamin D levels should be conducted, especially for elderly patients or those taking specific other medications, kidney function should be monitored periodically. This drug should not be mixed with other medications and should only be taken orally, never as an injectable form. Pregnant or breastfeeding women should be cautious when taking this drug, especially during the first six months of pregnancy, and it should only be taken when the benefits outweigh the risks based on a doctor’s judgment.

Serious side effects

Arrhythmias, hypercalcemia, hypercalciuria, kidney disease, severe edema with elevated blood pressure.

Mild side effects

Headache, weakness, fatigue, muscle pain, loss of appetite, weight loss, growth retardation, nausea, vomiting, constipation, diarrhea, polydipsia, polyuria, dehydration, high blood pressure, calcium stones, calcification of renal and vascular tissues, kidney disease, excessive bone calcification, arrhythmias, mental symptoms, awareness disorders, joint pain, myasthenia, drowsiness, azotemia, hypersensitivity reactions, thirst, confusion, bloating, abdominal pain, metallic taste, dry mouth, rash, itching, hypercalcemia.

This drug must be stored in a tightly closed container to avoid exposure to air and light, at a cool room temperature between 1 and 30 degrees. Proper storage preserves the effectiveness and prevents degradation of the drug.

Appearance

The contents are cholecalciferol emulsion that is yellowish with a colorless to green hue contained in a brown glass bottle.

Package unit

2.5 mL/bottle