Glofenac Injection (Diclofenac Sodium)

Adult administration

Administer 75mg (1 ampoule) of diclofenac sodium deeply into the upper outer quadrant of the gluteal muscle once a day. In severe cases, it can be administered 75mg (1 ampoule) twice a day; in this case, alternating injections should be given on both sides of the buttocks. After the initial treatment period, it should be switched to tablets or suppositories. Dosage should be adjusted appropriately according to age, disease, and symptoms. To minimize cardiovascular adverse reactions of this medication.

This medication may cause gastrointestinal bleeding in individuals who regularly consume more than three glasses of alcohol daily; therefore, it is important to consult with a physician or pharmacist. It can increase the risk of cardiovascular disease, so caution is necessary for those with a history of heart disease or stroke or those with risk factors. It can cause serious gastrointestinal problems such as gastrointestinal bleeding, ulcers, and perforation, so the elderly or those with a history of gastrointestinal disease should be careful. If allergic reactions are severe, it may cause myocardial infarction; therefore, it is important to immediately consult medical personnel if symptoms of hypersensitivity occur. This medication may be dangerous for premature infants due to certain components; therefore, preparations containing benzyl alcohol should not be administered to newborns or premature infants. Ampoule injections carry a risk of glass particle contamination; hence, caution is advised during use, particularly for children and the elderly. It is safe not to take this medication if you have peptic ulcers, severe blood disorders, liver dysfunction, kidney dysfunction, hypertension, or heart failure. Those with asthma or allergies to aspirin or other non-steroidal anti-inflammatory drugs should also avoid this medication. This medication should be used at the minimum effective dose for the shortest duration possible, and regular blood tests and liver and kidney function tests are needed for long-term use. Co-administration with other non-steroidal anti-inflammatory drugs or certain medications may increase the risk of side effects; hence, caution is required during combined use. During pregnancy, especially in the late stages, it may pose risks to the fetus, so use should be avoided, and if breastfeeding, it should be considered to stop nursing or discontinue the medication, as it can affect the baby through breast milk. Children and the elderly should be administered the minimum dose cautiously, with close monitoring for the occurrence of adverse reactions. In the case of overdose, symptoms such as hypotension, renal failure, seizures, and gastrointestinal disorders may appear, requiring immediate treatment.

Serious side effects

Hives, severe swelling (edema), chest tightness, difficulty breathing, cold sweat, pallor, severe rash with fever, blisters, skin shedding, pain in the mucous membranes of the mouth/eyes, shortness of breath or difficulty breathing, asthma attack, cough with fever accompanied by breathing difficulties, yellowing of the skin or eyes (jaundice), extreme lethargy, sudden and very severe headache, thunderclap headache, seizures, confusion of consciousness, visual disturbances, paralysis, urination.

Mild side effects

• Rarely
• it may cause peptic ulcers
• gastrointestinal bleeding
• esophageal ulcers
• perforation
• agranulocytosis
• hemoglobin decrease
• leukopenia
• thrombocytopenia
• anemia

This medication may be sensitive to light and should be stored in a container that does not let light in. It is recommended to maintain a storage temperature between 1 to 30 degrees Celsius. Proper storage helps maintain the medication's effectiveness and safety.

Appearance

Brown ampoule containing a colorless, transparent liquid

Package unit

2ml/ampoule x 1, 2ml/ampoule x 50