Medication info
Levotitan Tablet 40/5 mg

Levotitan Tablet 40/5 mg

Prescription medicationTablet경구
Ingredient · strength
Telmisartan Powder 23.9%›167.36mg / 1 tabletAmlodipine Besylate›6.935mg / 1 tablet
Manufacturer / importer
안국약품(주)
Appearance
This is a white and light gray, double-convex oval tablet.
Packaging
30 tablets/box [10 tablets/PTP X 3]
Approval status
Active

MFDS item code 201606820 · Approved 2016.11.30 · Insurance code 650204740

Summary

Main use
Improvement of Blood Pressure Control in Essential Hypertension
Who takes it
Adults · Children
Adult dose
The recommended dosage of this medication is one tablet once daily, to be taken with water, regardless of meals. It is advisable to take it at the same time each day (e.g., in the morning). In cases of severe renal impairment, treatment should start at a lower dosage, with gradual dose adjustments. Mild to moderate liver impairment: the daily dose of telmisartan should not exceed 40 mg. In elderly patients aged 75 years and older, starting at a low dosage is recommended.
Child dose
The safety and efficacy of this medication in pediatric patients under 18 years old have not been established; therefore, its use is not recommended.

Ingredients

Manufacturer
안국약품(주)

Efficacy & effects

Improvement of Blood Pressure Control in Essential Hypertension

  • Essential Hypertension
View approved original text

This medication helps lower blood pressure more effectively by using both medications together when blood pressure in patients with essential hypertension is not sufficiently controlled by either amlodipine or telmisartan alone. It is used to manage blood pressure reliably, thus reducing the risk of cardiovascular diseases and preserving health.

How to take

Adult dose

The recommended dosage of this medication is one tablet once daily, to be taken with water, regardless of meals. It is advisable to take it at the same time each day (e.g., in the morning). In cases of severe renal impairment, treatment should start at a lower dosage, with gradual dose adjustments. Mild to moderate liver impairment: the daily dose of telmisartan should not exceed 40 mg. In elderly patients aged 75 years and older, starting at a low dosage is recommended.

Child dose

The safety and efficacy of this medication in pediatric patients under 18 years old have not been established; therefore, its use is not recommended.

Precautions

This medication can pose serious risks to the fetus during pregnancy, especially in the second and third trimesters, and should not be taken by pregnant women or women who may become pregnant. This medication should not be administered to patients with certain medical conditions, such as severe liver impairment, patients with heart failure or heart problems, and patients with hypotension, among others. Patients with primary aldosteronism, certain heart valve diseases, liver impairment, gastrointestinal diseases, kidney problems, and the elderly should use this medication with caution. Side effects like dizziness or peripheral edema may occur frequently, and serious side effects may occur rarely, so if any abnormal symptoms arise, it is essential to consult a healthcare professional immediately. This medication should be avoided during pregnancy, and if pregnancy is confirmed, it should be discontinued as soon as possible, with a switch to alternative therapies. Due to the risk of hypotension, patients with fluid or salt deficiency should improve their condition before taking this medication and monitor their blood pressure closely during treatment. There is a risk of hyperkalemia, so regular monitoring of blood potassium levels is necessary, and caution is needed when used with potassium supplements or medications containing potassium. Patients with weakened kidney function should frequently check their kidney function and electrolyte status while taking this medication. This medication can interact with other antihypertensive agents or specific drugs, so patients must inform their healthcare provider of any other medications they are taking. Breastfeeding women should avoid taking this medication and it is not recommended for children or adolescents under 18 years of age. In case of overdose, hypotension, dizziness, and heart-related issues may arise; therefore, strict adherence to the prescribed dosage is crucial, and if any unusual symptoms occur, a visit to the hospital should be made immediately. This medication should be stored in a container that can block light and kept out of reach of children, and packaging should only be opened immediately prior to use.

Side effects and when to seek care immediately

Serious side effects

  • Sepsis
  • thrombocytopenia
  • anaphylaxis
  • syncope
  • myocardial infarction
  • ventricular tachycardia
  • arrhythmia
  • atrial fibrillation
  • vasculitis
  • dyspnea
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  • hepatitis
  • jaundice
  • increased liver enzymes
  • angioedema (potentially fatal)
  • erythema multiforme
  • exfoliative dermatitis
  • Stevens-Johnson syndrome
  • toxic epidermal necrolysis
  • intestinal vascular edema
  • acute renal failure
  • congestive heart failure
  • hepatocellular carcinoma
  • cerebral infarction

Mild side effects

  • Dizziness
  • peripheral edema
  • upper respiratory infection
  • urinary tract infection
  • anemia
  • hyperkalemia
  • hypoglycemia
  • hyponatremia
  • hyperglycemia
  • depression
Show 28 more
  • insomnia
  • mood changes
  • drowsiness
  • migraine
  • headache
  • sensory disturbances
  • visual impairment
  • vertigo
  • tinnitus
  • palpitations
  • bradycardia
  • tachycardia
  • flushing
  • hypotension
  • orthostatic hypotension
  • cough
  • rhinitis
  • changes in bowel habits
  • abdominal pain
  • indigestion
  • nausea
  • vomiting
  • dry mouth
  • itching
  • sweating
  • rash
  • hair loss
  • purpura

Not everyone experiences these, and they can vary from person to person.

Storage

This medication should be stored in a tightly sealed container that can block light, at room temperature between 1°C and 30°C. This storage method helps maintain the medication's efficacy and safety.

Appearance and packaging

Appearance

This is a white and light gray, double-convex oval tablet.

Package unit

30 tablets/box [10 tablets/PTP X 3]

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

Questions about this medicine

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For anything that needs medical judgment, consult a doctor or pharmacist.

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.